It is common to notice changes in a dog's urination pattern in the first 24 to 48 hours after TPLO surgery.

Most of these changes are temporary and related to the effects of anesthesia, pain medications, and reduced mobility.

However, not urinating at all for more than 12 to 24 hours is a clinical concern that requires prompt veterinary contact.

Quick answer: Reduced urination in the first 12 to 24 hours after TPLO is usually caused by anesthesia effects, opioid medications, pain, or stress. Contact your vet immediately if your dog has not urinated within 12 hours post-surgery, or if you observe straining, vocalization, or abdominal distension.

Key takeaways

• Reduced urination in the first 12 to 24 hours is normal: anesthesia suppresses bladder awareness and opioids reduce the sensation of fullness
• Contact your vet if no urination occurs within 12 hours post-surgery: this is the critical threshold, per published veterinary guidance do not wait
• Straining, vocalizing, or abdominal swelling requires same-day veterinary evaluation: these signs suggest urinary retention requiring catheterization
• Opioid pain medications are the most common pharmacological cause: they reduce bladder filling sensation and sphincter tone in some dogs
• Surgical catheterization during the procedure may temporarily affect urination for 12 to 24 hours after catheter removal
• Increased water intake without urination is particularly concerning: it suggests the dog is producing urine but cannot eliminate it a potential retention emergency

Why dogs may not urinate normally after TPLO

Anesthesia effects

General anesthesia suppresses the entire nervous system, including the neural pathways that signal bladder fullness and initiate voiding.

As anesthetic agents clear over the first 12 to 24 hours, normal bladder signaling gradually returns.

Most dogs produce less urine during anesthesia because of reduced blood pressure and fluid redistribution.

When fluid therapy resumes and hydration normalizes after surgery, urine production increases but the dog must also have recovered enough neurological function to void normally.

Opioid pain medications

Opioid analgesics (hydromorphone, morphine, buprenorphine) prescribed after TPLO affect urination in two main ways.

They reduce the perception of bladder fullness, so the dog does not signal readiness to urinate as promptly as usual.

In some dogs they also increase urethral sphincter tone, making voiding more difficult.

JustAnswer veterinary consultation confirms: opioids can cause urinary retention by relaxing or altering bladder muscles, making it hard for the dog to pee.

This effect is temporary and typically resolves as opioid dosing decreases over the first 48 to 72 hours.

Pain and reluctance to posture

Urination requires the dog to posture squatting or lifting a leg both of which require hindlimb use and core stability that are painful in the first days after TPLO.

A dog that finds posturing too painful may suppress the urge to urinate or produce only small amounts.

Providing a non-slip surface, a low slung outdoor space (not steps or slopes), and supporting the dog with a belly sling during outdoor trips reduces posturing pain and encourages normal urination.

Surgical catheterization

A urinary catheter is often placed during TPLO surgery to drain the bladder, keep the surgical field dry, and prevent accidents during the procedure.

After catheter removal, some dogs take 12 to 24 hours to resume normal voiding patterns as the urethra recovers from catheter placement and the bladder regains normal tone.

Stress and unfamiliar environment

Dogs in pain, in an unfamiliar post-surgical environment, and wearing an E-collar may suppress urination due to stress.

Stress-related urinary suppression is temporary and usually resolves as the dog settles into the home recovery environment.

Normal urination expectations after TPLO

Most dogs urinate at least once within 6 to 12 hours of returning home from surgery. By 24 hours, most dogs have urinated multiple times.

The SustainableVet.org dog-not-peeing guide confirms: if your dog does not pee within 24 hours post-surgery, contact your veterinarian immediately to rule out complications.

The published veterinary guidance for emergency contact is: no urination within 12 hours post-surgery contact your vet.

Signs that require immediate veterinary contact

Contact your veterinarian same-day or go to an emergency clinic if you observe:

No urination at all for 12 or more hours after surgery: this is the key threshold do not wait to see if it resolves

Straining or crying during urination attempts: the dog is trying to urinate but cannot produce a stream classic urinary retention sign

Abdominal distension: the belly feels full or tense; this suggests a distended bladder (urinary retention emergency)

Drinking water but producing no urine: urine is being produced but cannot be eliminated urgent

Vomiting or lethargy alongside no urination: systemic signs accompanying urinary retention indicate a more serious emergency

Urinary retention: what happens and how it is treated

Urinary retention means the bladder cannot empty. The bladder fills progressively and becomes painful, distended, and eventually at risk of rupture if unrelieved. Prolonged retention also causes back-pressure on the kidneys.

Treatment depends on the cause:

• Catheterization: gentle placement of a urinary catheter to drain the bladder provides immediate relief and allows the bladder to recover normal tone
• Pain management adjustment: if opioid-induced retention is suspected, the analgesic protocol may be modified
• Bethanechol: a parasympathomimetic drug that stimulates bladder contraction; sometimes used in dogs with neurogenic urinary retention
• Urinalysis and culture: if infection is suspected alongside retention

Home care to encourage urination

• Scheduled outdoor trips every 2 to 4 hours for the first 24 to 48 hours
• Non-slip surface outdoors pain and weakness increase slipping risk
• Gentle belly-sling support to reduce posturing pain (fold a large towel under the belly and lift slightly)
• Quiet, calm outdoor environment stressed dogs suppress urination
• Adequate pain control contact your vet if your dog is vocalizing or reluctant to move; these are signs pain medication is insufficient
• Monitor and record each urination: time, approximate volume, any straining or discomfort

For the related incontinence guide (opposite problem), see dog incontinence after TPLO surgery: causes and care. For the post-surgical pain guide, see dog whining after TPLO surgery: causes and care.

For the full recovery guide, see what to expect after TPLO surgery in dogs. For the monitoring guide during early recovery, see post-operative care mistakes increasing TPLO infection risk.

Frequently asked questions

How long after TPLO surgery should my dog urinate?

Most dogs urinate within 6 to 12 hours of returning home from surgery. Contact your veterinarian if no urination has occurred within 12 hours.

Do not wait for the 24-hour mark if the dog is straining, vocalizing, or appears uncomfortable.

My dog is drinking water but not peeing at all. Is this an emergency?

Yes. A dog that is drinking and producing urine but cannot eliminate it (retention) needs same-day veterinary evaluation. A distended bladder is painful and can rupture.

Do not manage this at home contact your vet immediately.

Can opioid pain medications cause urinary retention?

Yes. Opioids are a recognized cause of urinary retention in both humans and dogs.

If your dog was urinating normally before surgery and stops after receiving opioid medications, this is likely a contributing factor.

Contact your vet the analgesic protocol may be modified without eliminating pain management.

What does a catheter placement during surgery do to urination afterward?

Urinary catheters are placed during TPLO to drain the bladder and keep the surgical field dry.

After catheter removal, some dogs take 12 to 24 hours to resume normal voiding as the urethra recovers.

This is expected and not a cause for alarm, as long as the dog urinates within the normal timeframe.

Is it safe to give my dog extra water if they're not peeing?

Normal hydration is essential and should be maintained. Do not restrict water.

However, if the dog is drinking normally and still not producing urine, this increases the urgency of veterinary contact rather than reducing it.

Resources

• VCA Animal Hospitals. Tibial Plateau Leveling Osteotomy (TPLO) in Dogs. vcahospitals.com
• TPLO Info. Recovery FAQs. tploinfo.com
• PetMD. Urinary Retention in Dogs. petmd.com
• Midwest Veterinary Specialists. Post-Operative Care Following TPLO. midwestveterinaryspecialists.com

Age alone does not disqualify a dog from TPLO surgery.

The decision for an older or senior dog depends on overall health status, concurrent conditions, quality of life goals, and individual assessment -- not a chronological cutoff.

Many senior dogs benefit substantially from TPLO, while some older dogs are better managed conservatively. Understanding how to approach this decision is essential.

Quick answer: TPLO is viable for most older dogs with CCL rupture who are medically suitable for anesthesia. Published data estimates 85 to 90% of senior dogs regain near-normal or improved limb function. Age increases anesthetic risk and slows recovery -- manageable factors, not contraindications. Pre-surgical bloodwork and cardiac evaluation reduce risk.

Key takeaways

• Age alone is not a contraindication for TPLO: a comprehensive veterinary assessment is essential; the decision is based on health status, not chronological age
• 85 to 90% of senior dogs regain near-normal or improved limb function: comparable to the 90 to 95% general TPLO population; older dogs achieve similar success with appropriate post-operative care
• The primary risk factors for senior dogs are anesthetic risk and comorbidities: older dogs are more likely to have heart disease, kidney disease, or arthritis complicating anesthesia; pre-surgical screening manages these risks
• Recovery takes longer in older dogs: senior dogs need a longer recovery with extra monitoring and rehabilitation; timelines should be extended and expectations adjusted
• Conservative management is appropriate for some older dogs: very elderly dogs with limited activity needs, multiple health concerns, or advanced concurrent arthritis may benefit more from conservative management
• The quality of life cost of not operating is significant: untreated CCL rupture means chronic joint pain, progressive arthritis, and severe mobility impairment; TPLO offers a better quality of remaining life for many senior dogs

What changes with age in TPLO candidates

Anesthetic risk

General anesthesia in older dogs carries higher risk than in young adults. The primary reasons:

Cardiovascular function: cardiac output typically decreases with age. Dogs with occult cardiomyopathy, valve disease, or arrhythmias have reduced ability to compensate for the cardiovascular demands of general anesthesia. Pre-surgical cardiac evaluation (auscultation, chest radiographs, echocardiography if indicated) identifies and quantifies this risk.

Renal function: anesthesia and NSAIDs both affect renal perfusion. Dogs with reduced GFR are at risk for acute kidney injury. Pre-surgical blood chemistry (BUN, creatinine, SDMA) establishes baseline renal function and guides anesthetic protocol choices.

Hepatic function: the liver metabolizes most anesthetic agents. Hepatic insufficiency prolongs drug effect and increases toxicity risk. Pre-surgical liver enzyme panel and bile acids test if enzymes are elevated.

Thermoregulation: older dogs lose body heat more quickly during anesthesia. Active warming protocols (circulating warm water blankets, warm IV fluids, warm recovery environment) are particularly important.

Healing and regeneration

Bone healing takes longer in older dogs. The osteotomy that consolidates in 8 weeks in a 3-year-old Labrador may take 10 to 14 weeks in a 10-year-old dog.

Radiographic confirmation of healing before lifting restrictions is therefore even more critical in senior dogs.

Muscle rebuilding is also slower. Full muscle recovery may take 6 to 9 months rather than 4 to 6 months in older dogs.

Pre-existing arthritis

Most older dogs with CCL disease have concurrent arthritis in the affected stifle at the time of presentation.

This does not prevent TPLO from providing benefit, but it affects the baseline from which the dog recovers.

Upland Animal Hospital confirms: dogs with advanced degenerative joint disease may not be ideal candidates; existing joint damage could limit improvement in mobility.

The realistic expectation is not a return to young-dog mobility, but elimination of instability pain and slowing of further arthritis progression -- both of which meaningfully improve quality of life.

Pre-surgical assessment for older dogs

The pre-surgical workup for a senior dog should include:

Complete blood count: rule out anemia, infection, and thrombocytopenia.

Blood chemistry panel: kidney function (BUN, creatinine, SDMA), liver function (ALT, ALP, GGT), albumin, glucose.

Urinalysis: assess renal concentrating ability and rule out urinary tract infection (a source of bacteremia that can seed the implant).

Chest radiographs: assess cardiac silhouette and pulmonary fields for occult cardiac disease or pulmonary abnormalities.

Electrocardiography: if cardiac auscultation reveals arrhythmia or murmur.

Echocardiography: if the cardiac evaluation suggests significant structural disease; quantifies severity and guides anesthetic protocol.

Blood pressure: hypertension is common in older dogs and affects anesthetic management.

Companion Animal Hospital confirms: older patients are more likely to have heart disease, kidney problems, or arthritis complicating anesthesia and recovery. Each patient is evaluated thoroughly to weigh complications against expected benefits.

When TPLO is appropriate for older dogs

TPLO is generally appropriate when:

• Pre-surgical assessment confirms the dog is medically suitable for general anesthesia
• The dog has a good quality of life before the CCL rupture
• The owner is committed to the post-operative care demands
• Life expectancy is at least 1 to 2 years (enough time to benefit from the recovery period)
• Pain from CCL instability is significantly reducing the dog's quality of life

SustainableVet.org confirms: 85 to 90% of senior dogs regain near-normal or improved limb function. Older dogs achieve similar success rates when conditions like arthritis are managed well.

When conservative management may be more appropriate

Conservative management (strict rest, NSAIDs, physical therapy, weight management) may be more appropriate when:

• The dog has severe concurrent cardiac, renal, or hepatic disease that significantly elevates anesthetic mortality risk
• Pre-existing arthritis is so advanced that functional improvement from TPLO is unlikely
• The dog has very limited mobility needs (sedentary older dog in minimal pain before the CCL event)
• Life expectancy is significantly limited by a concurrent condition

Chewy confirms: TPLO can be performed in dogs of any age, but your veterinarian will consider overall health in senior dogs.

Upland Animal Hospital confirms: very elderly dogs might benefit more from conservative management if they have limited activity needs and multiple health concerns.

Adjusting expectations and the recovery plan for older dogs

For older dogs undergoing TPLO:

• The restriction period is the same (8 to 12 weeks) but radiographic healing may take longer; follow-up imaging should be extended if healing is not confirmed at the standard 6 and 12 week timepoints
• Recovery plans should include additional physiotherapy support, hydrotherapy, and pain management beyond the standard protocol
• Concurrent arthritis management (joint supplements, periodic NSAIDs, hydrotherapy) continues long-term after recovery
• Body condition monitoring is critical -- older dogs are more likely to gain weight during restriction

SustainableVet.org confirms: senior dogs need a longer recovery with extra monitoring and rehabilitation. Physical therapy helps, but patience and adjusted expectations are essential.

For the surgery overview, see what is TPLO surgery in dogs?. For recovery, see post-surgery recovery after TPLO in dogs. For long-term outcomes, see long-term outcomes of TPLO surgery.

For anesthesia protocol, see TPLO anesthesia protocol in dogs.

Frequently asked questions

My dog is 11 years old with a torn CCL. Should I get TPLO?

Age 11 is not a contraindication. The decision depends on your dog's overall health. Schedule a thorough pre-surgical assessment including bloodwork, urinalysis, and chest radiographs.

If your dog is medically suitable for anesthesia and has a reasonable life expectancy, TPLO will likely provide a better quality of remaining life than conservative management of an unstable stifle.

Does TPLO take longer to heal in older dogs?

Yes. Bone healing in older dogs typically takes 2 to 4 weeks longer than in young adults.

Muscle recovery also takes longer -- expect 6 to 9 months rather than 4 to 6 months. Radiographic follow-up should reflect this extended timeline.

Is the anesthetic risk for TPLO too high in senior dogs?

This depends entirely on the individual dog's health status. Pre-surgical assessment quantifies anesthetic risk. Many senior dogs in good health tolerate TPLO anesthesia well.

Dogs with significant cardiac or renal disease have elevated risk that must be weighed against the benefit of surgical stabilization. There is no population-level answer -- only individual assessments.

Can conservative management work for an older dog with CCL rupture?

For some older dogs, yes.

For most medium and large dogs over 15 kg with complete CCL rupture, conservative management does not restore normal joint stability, and chronic pain with progressive OA is the expected outcome.

Whether conservative management is appropriate depends on the dog's baseline activity level, severity of rupture, concurrent health status, and owner goals.

What is the recovery quality like for older dogs after TPLO?

With appropriate rehabilitation and arthritis management, most older dogs achieve meaningful improvement in mobility and pain control after TPLO.

The realistic goal is not the function of a young adult dog but rather elimination of the pain of joint instability and a return to comfortable daily activity.

SustainableVet.org confirms: when combined with weight management and physical therapy, TPLO offers lasting relief, often keeping dogs active well into their senior years.

Resources

• SustainableVet. TPLO Surgery for Older Dogs. sustainablevet.org
• Companion Animal Hospital Maize. Senior Dogs and TPLO. maizevet.com
• Upland Animal Hospital. What Is TPLO Surgery in Dogs? uplandanimalhospital.com
• ACVS. Cranial Cruciate Ligament Disease. acvs.org

TPLO produces predominantly positive long-term effects in most dogs, but it also produces a predictable set of changes that owners should understand and manage proactively.

Most of these effects are manageable with appropriate care. Knowing what to expect prevents owners from being surprised by normal post-TPLO findings and helps them recognize when a change requires veterinary attention.

Quick answer: The 13 key long-term effects of TPLO surgery: improved joint stability, progressive osteoarthritis, muscle atrophy, morning stiffness, cold weather sensitivity, scar tissue formation, patellar tendon thickening, permanent implant in situ, contralateral CCL rupture risk, late implant complications, behavioral changes from chronic pain, weight management challenges, and long-term monitoring requirements.

Key takeaways

• Improved joint stability is the intended and most common long-term effect: for 90 to 95% of dogs, TPLO eliminates CCL-related instability and restores near-normal function
• Progressive osteoarthritis develops in all CCL-affected stifles regardless of surgical technique: TPLO slows OA progression but does not stop it; long-term OA management is a universal requirement
• Muscle atrophy is common in the operated leg throughout recovery; the thigh may remain visibly smaller than the contralateral side for months if rehabilitation is inadequate
• Contralateral CCL rupture risk is high: SustainableVet.org confirms up to a 50% chance of tearing the opposite CCL within a few years; the same degenerative process affects both stifles
• The TPLO plate and screws are permanent in the vast majority of cases: removal is only performed when complications arise; routine plate removal is not standard practice
• Weight management is the most impactful long-term owner-controlled variable: excess weight accelerates OA progression; maintaining ideal body condition is the primary long-term prevention strategy

The 13 long-term effects

1. Improved joint stability and mobility

The primary intended effect. The osteotomy and plate fixation permanently change the tibial plateau geometry, eliminating the cranial tibial thrust that caused instability.

For 90 to 95% of dogs, this produces lasting functional improvement: return to normal gait, ability to run and play, and freedom from the pain of unstable joint loading.

SustainableVet.org confirms: over 90% of dogs regain full limb function within a year; with proper care, many dogs remain active for 8 to 10 years after surgery.

2. Progressive osteoarthritis

The most universal long-term challenge. CCL disease initiates an arthritis process in the stifle that continues regardless of surgical outcome.

TPLO reduces the rate of progression and the severity of clinical signs compared to other treatment options, but OA continues.

Clinical signs of progressing OA emerge gradually over months and years: stiffness after rest, reluctance to run, difficulty climbing, and behavioral changes associated with chronic low-grade pain.

Management: weight management, omega-3 fatty acids, glucosamine and chondroitin, NSAIDs for flares, hydrotherapy, physiotherapy.

3. Muscle atrophy and asymmetry

The operated leg loses muscle mass rapidly during the restriction period and slowly rebuilds during rehabilitation. Full recovery of muscle symmetry takes 4 to 6 months in most dogs.

In some dogs -- particularly those with inadequate rehabilitation or ongoing joint pain -- visible thigh circumference asymmetry persists long-term.

Vetplayas confirms: due to reduced use during recovery and altered movement patterns post-surgery, muscles around the operated leg may weaken and shrink.

4. Morning stiffness

Morning stiffness -- the dog rises from sleep stiffly and walks awkwardly for the first few minutes before loosening up -- is one of the most common long-term effects of post-TPLO OA.

It typically develops months to years after surgery and gradually worsens as the dog ages.

This stiffness should not be confused with acute lameness. It consistently improves within 5 to 10 minutes of movement.

If it does not improve, or if the dog refuses to bear weight on waking, contact your vet.

5. Cold weather sensitivity

Dogs with OA in the operated stifle commonly show increased stiffness and lameness during cold weather or when barometric pressure changes.

This reflects the sensitivity of arthritic joints to temperature and pressure changes -- the same phenomenon seen in human arthritis.

Management: NSAIDs or joint supplements maintained year-round; warming the dog's sleeping area; a brief gentle walk before expecting full function in cold conditions.

6. Scar tissue formation

The surgical dissection and bone healing produce scar tissue in and around the stifle. This fibrous tissue generally has a beneficial stabilizing effect, contributing to long-term joint stability.

In some dogs, however, periarticular fibrosis restricts range of motion and causes stiffness that persists long after bone healing is complete.

Regular low-impact exercise and physiotherapy help maintain range of motion and prevent excessive fibrous tissue restriction.

7. Patellar tendon thickening

Fibrous thickening of the patellar tendon is a recognized long-term change after TPLO. It is typically subclinical -- detected on palpation at follow-up examinations but not producing clinical lameness.

In a small number of dogs, it contributes to reduced range of motion.

8. Permanent implant in situ

The TPLO plate and screws are designed to remain in place for life. In the vast majority of dogs, the implant is never removed and causes no long-term problems.

SustainableVet.org confirms: these implants are meant to stay in place permanently. In rare cases, some dogs may develop infections around the implant or experience loosening of the hardware over time.

The plate is palpable under the skin on the medial tibial surface. This is normal and not a complication.

9. Contralateral CCL rupture

The degenerative process that caused one CCL to rupture typically affects both stifles.

SustainableVet.org confirms dogs have up to a 50% chance of tearing the CCL in the opposite knee within a few years.

RCVS confirms approximately 50% of dogs develop CCL disease in the other hind limb.

This is not a complication of TPLO -- it is the natural history of bilateral CCL disease.

Monitoring the contralateral stifle for early signs of instability, effusion, or lameness is appropriate in all TPLO dogs.

10. Late implant-associated complications

Implant-related complications -- loosening, late infection from hematogenous seeding, or implant irritation -- can occur years after the original surgery. These are uncommon but recognized long-term effects.

Signs: new lameness focused at the plate site, warmth or swelling over the plate, a new draining tract in previously healed skin. Any of these warrants prompt veterinary assessment.

11. Behavioral changes

Chronic joint pain from progressive OA, late meniscal injury, or implant irritation can produce subtle behavioral changes: reduced engagement in play, reluctance to walk, increased irritability, or reduced stair use.

These changes are often attributed to aging but may reflect treatable pain.

Annual or semi-annual pain assessments, including use of validated canine pain scales (Canine Brief Pain Inventory, Helsinki Chronic Pain Index), help detect behavioral pain signs before they become severe.

12. Weight management challenges

Activity restriction during recovery predisposes many dogs to weight gain. Excess weight gained during the 8 to 12 week restriction period is then carried on the healing joint for the following months.

Long-term obesity accelerates OA progression and is the most modifiable risk factor for long-term joint health.

Medcovet confirms: because activity is restricted, veterinary teams may recommend reducing food intake by about 30% during recovery to prevent weight gain and extra strain on the knee joint.

13. Long-term monitoring and supplement requirements

TPLO dogs benefit from long-term monitoring (every 6 to 12 months after full recovery) to assess:

• Arthritis progression radiographically and clinically
• Body condition score and weight
• Contralateral stifle stability
• Implant integrity (radiographs every 1 to 2 years in some protocols)

Joint supplements (omega-3 fatty acids at anti-inflammatory doses; glucosamine and chondroitin) and ongoing weight management are the primary preventive interventions for the long-term joint changes that TPLO does not prevent.

For the long-term outcomes guide, see long-term outcomes of TPLO surgery. For arthritis management, see arthritis after TPLO surgery in dogs.

For the signs that require attention, see signs of TPLO failure in dogs. For the failure rate overview, see TPLO failure rate in dogs.

Frequently asked questions

Will my dog develop arthritis even if the TPLO was successful?

Yes. All CCL-affected stifles develop progressive osteoarthritis regardless of surgical technique or outcome.

TPLO reduces the rate of progression and the severity of clinical signs compared to non-surgical management and lateral suture repair.

The goal of TPLO is not to prevent OA but to minimize it while restoring function.

How long will the TPLO plate last?

The plate is designed to be permanent. Published long-term follow-up data at 6.8 years shows 90.4% of dogs with good to excellent results -- with the plate in place.

Plate complications requiring removal occur in 3.5 to 7.5% of cases.

My dog had TPLO 2 years ago and is now limping. Is this related to the surgery?

Possibly. Two-year post-TPLO lameness most commonly results from progressive OA, late meniscal tear, late implant-associated infection (hematogenous seeding), or contralateral CCL disease.

A veterinary examination and radiographs of both stifles will identify the cause and guide treatment.

Does the opposite leg always need TPLO as well?

Not necessarily and not always at the same time. RCVS confirms approximately 50% of dogs develop CCL disease in the opposite hind limb.

When and whether the second stifle requires surgery depends on whether the second CCL has ruptured or become significantly unstable. Annual monitoring of the contralateral stifle is appropriate.

Can TPLO dogs still live active lives long-term?

Yes. Most do. SustainableVet.org confirms that with proper care, many dogs remain active for 8 to 10 years after surgery.

The keys are weight management, regular low-impact exercise, joint supplements, and addressing pain or complications promptly.

Resources

• SustainableVet. 13 Long-Term Effects of TPLO Surgery on Dogs. sustainablevet.org
• RCVS Canine Cruciate Registry. Tibial Plateau Levelling Osteotomy. rcvsknowledge.org
• TPLO Info. TPLO Literature and Studies. tploinfo.com
• SustainableVet. Long-Term Outcomes of TPLO Surgery. sustainablevet.org

TPLO recovery is a structured, staged process. The surgery corrects the mechanical cause of CCL instability, but the bone, soft tissue, and muscle need weeks to months to rebuild around that correction.

Understanding what is required at each stage -- and what signs require prompt veterinary contact -- is as important as the surgery itself.

Quick answer: Post-TPLO recovery requires 8 to 12 weeks of structured activity restriction for bone healing, followed by progressive rehabilitation. Key milestones: 2-week incision recheck; 6-week radiographic assessment; 12-week final radiograph and activity clearance. Warning signs requiring same-day contact: sudden non-weight bearing, spreading redness or discharge, fever, or worsening lameness.

Key takeaways

• The first 2 weeks are the most critical: the osteotomy has no mechanical strength; jumping, running, or slipping can displace the plate; crate rest with bathroom leash walks only is non-negotiable
• Most dogs begin toe-touching within 24 to 48 hours of surgery: early weight bearing maintains muscle mass and stimulates bone healing; it does not indicate readiness for more activity
• Cold therapy for the first 3 to 5 days significantly reduces swelling and pain: 10 to 15 minutes of wrapped ice pack applied 3 to 4 times daily is the most effective owner-administered early intervention
• The 6-week radiograph is the gate for activity increase: bone healing cannot be confirmed clinically; radiographic assessment is the only reliable confirmation of osteotomy progression
• Full muscle recovery takes 4 to 6 months: bone healing at 12 weeks and full functional recovery are different endpoints
• Reducing food intake by approximately 30% during recovery prevents weight gain that stresses the healing osteotomy; activity restriction rapidly leads to weight gain without dietary adjustment

Immediate post-operative period: the first 24 to 48 hours

Coming home

Most dogs are discharged 24 to 48 hours after TPLO, though same-day discharge protocols exist at some facilities.

The dog will be sedated, disoriented from anesthesia, and may have bandaging on the surgical leg. Expect:

• Grogginess and disorientation for 12 to 24 hours from anesthesia
• Some whining or restlessness (often anesthesia effect, not pain)
• Refusal to bear weight or toe-touching only
• Mild to moderate swelling around the incision, peaking at days 2 to 5

Setting up the recovery space

Before the dog arrives home, have in place:

• A correctly sized crate in the main living area
• Non-slip mats or yoga mats over all hard flooring
• Soft, washable bedding in the crate
• Water and food at floor level
• Baby gates blocking stairs
• Medications filled and ready

Medications: first day priorities

Give prescribed medications on the schedule provided at discharge. NSAIDs (meloxicam, carprofen) require food. Gabapentin causes sedation -- this is expected and helps with pain and anxiety in the first days.

Never skip doses or give extra without veterinary guidance.

Week-by-week recovery overview

Weeks 1 to 2: incision healing phase

Activity: crate rest except for bathroom leash walks. Maximum 5-minute walks, 3 to 5 times daily. No stairs, no furniture, no running, no off-leash time.

E-collar: must be worn at all times except supervised eating. One licking episode can introduce S. pseudintermedius from the oral cavity directly into the incision.

Cold therapy: wrap an ice pack in a thin cloth; apply to the incision for 10 to 15 minutes; 3 to 4 times daily; begin day 1 and continue through days 3 to 5.

Incision inspection: check the incision daily at a consistent time. Normal healing: redness fading from day 5, no discharge after day 3, clean approximated wound edges. Concerning: spreading redness, cloudy or malodorous discharge, wound dehiscence.

Weight management: Medcovet recommends reducing food intake by approximately 30% during the restriction period to prevent weight gain from inactivity.

2-week recheck: incision assessment, suture or staple removal if healing is confirmed, pain management review, early mobility assessment.

Weeks 3 to 6: progressive walking phase

Activity: leash walk duration increases -- by up to 5 minutes per week from the week 2 baseline. No off-leash, no running, no stairs without guidance.

Passive range-of-motion exercises: if the vet has approved, begin gentle flexion and extension of the stifle. 5 to 10 repetitions, 2 to 3 times daily. Prevents stiffness during the bone healing period.

Weight bearing: most dogs should be consistently bearing weight on the operated leg by weeks 3 to 4. Three-legged walking during activity is still common but should be decreasing.

Diet: maintain the reduced caloric intake until the vet clears increased activity.

Weeks 6 to 8: radiographic checkpoint

6-week radiograph: the single most important post-operative checkpoint. Images confirm whether the osteotomy is healing as expected. If healing is progressing, activity is increased. If healing is delayed, restrictions continue and the underlying cause is investigated.

After radiographic confirmation:

• Leash walks increase to 15 to 20 minutes
• Physiotherapy begins
• Controlled hill walking and balance work may begin

SustainableVet.org confirms: after the initial weeks of rest, swelling should decrease; gradual increase in leash walking should follow; physical therapy options include hydrotherapy, balance training, laser therapy, and massage.

Weeks 8 to 12: consolidation

10 to 12 week radiograph: confirms bone union. After radiographic confirmation of healing, activity restrictions are progressively lifted.

Return to activity: activity is reintroduced progressively over the following 4 to 6 weeks. No sudden full return to prior activity level.

Managing common post-operative issues

Swelling

Expected: peaks at days 2 to 5, resolves by 2 weeks. Ankle swelling from gravity-dependent fluid migration is normal at days 3 to 5.

Concerning: swelling that is not reducing after day 5, or that reappears after initial resolution.

Management: cold therapy in the first 3 to 5 days; elevation where possible; contact vet if swelling is not following the expected trajectory.

Pain and restlessness

Normal pain is controlled by the prescribed medication regimen and should consistently decrease over the first 2 weeks.

Uncontrolled pain (unable to settle, continuous crying, refusing all weight bearing beyond day 3) requires a vet call -- medication adjustment or a complication evaluation is needed.

Incision care

Do not clean the incision daily unless specifically instructed by your vet. Daily inspection is required; daily cleaning is not. If cleaning is needed, use only the vet-approved solution.

Constipation

Opioid pain medications commonly cause constipation in the first days. Discuss this with your vet at discharge -- they may recommend a stool softener if constipation becomes a concern.

Warning signs that require same-day veterinary contact

• Sudden complete non-weight bearing after a period of partial bearing
• Spreading redness beyond the incision margins
• Cloudy, yellow, green, or malodorous discharge from the incision
• Wound edges separating
• Fever (rectal temperature above 39.5 C / 103.1 F)
• Lameness worsening after a period of improvement (trajectory reversal)
• New swelling at the plate site (not the incision) after the second week
• Any systemic sign (lethargy, inappetence, fever) accompanying local wound changes

For the full recovery timeline overview, see what to expect after TPLO surgery in dogs. For confinement setup, see how to confine your dog after TPLO surgery.

For infection prevention, see TPLO incision infection: symptoms and prevention. For physical therapy timing, see when to start physical therapy after TPLO surgery.

Frequently asked questions

My dog is not using the leg at all 5 days after surgery. Is this normal?

Some dogs refuse to bear weight for the full first 2 weeks -- this is within the normal range.

If the dog was bearing some weight at days 2 to 3 and has now stopped completely, or shows signs of severe pain, contact your vet to rule out a complication.

Persistent non-weight bearing beyond 2 weeks warrants assessment.

When can my dog go back to sleeping in our bed?

Not during the restriction period. Jumping off the bed -- even once -- generates the same plate-failure risk as running.

The dog must sleep in the crate or on a floor-level dog bed for the full restriction period.

My dog is constantly trying to lick the incision. What can I do?

Ensure the e-collar is the correct size -- most dogs can reach their hind legs with a collar that is too small.

Try a longer cone or a recovery suit (medical pet shirt) as a supplement. Ask your vet about trazodone or gabapentin for anxiety driving the licking behavior.

Do not remove the e-collar to give the dog a break unless you are directly supervising and can prevent licking.

Can I give my dog human joint supplements during recovery?

Some human supplements (fish oil at appropriate doses) are safe. Others contain xylitol or other ingredients toxic to dogs. Never give a human supplement without explicit vet approval.

Veterinary-formulated joint supplements are the safer choice.

How do I know when recovery is complete?

Recovery is complete when: (a) the 12-week radiograph confirms bone union, (b) the vet clears full activity, and (c) the operated leg has regained near-symmetrical muscle mass (4 to 6 months).

Bone healing at 12 weeks is the legal clearance; full muscle recovery is the functional completion of recovery.

Resources

• SustainableVet. Post-Surgery Recovery After TPLO in Dogs. sustainablevet.org
• Medcovet. Essential Guide to Dog Recovery TPLO Surgery. medcovet.com
• TPLO Info. What to Expect After Your Dog's TPLO Surgery. tploinfo.com
• VCA Animal Hospitals. TPLO. vcahospitals.com

Cruciate ligament injuries are common in dogs, often requiring surgical repair to restore joint stability. The Synthes TPLO plate is a specialized orthopedic implant designed to support tibial plateau leveling osteotomy (TPLO) surgeries, which correct knee joint mechanics in affected dogs.

This article explains what the Synthes TPLO plate is, how it works, and why it is widely used in veterinary orthopedic surgery. You will learn about its design features, surgical application, and postoperative care to understand its role in successful cruciate ligament repair.

What is a Synthes TPLO Plate?

The Synthes TPLO plate is a metal implant used in veterinary surgery to stabilize the tibia after a TPLO procedure. It is specifically designed to fit the anatomy of a dog's tibia and support the bone during healing.

This plate helps maintain the new angle of the tibial plateau after osteotomy, allowing the knee to function without abnormal stress on the cruciate ligament.

• Purpose-built design: The plate is contoured to match the shape of the canine tibia, ensuring a precise fit and optimal stability during healing.
• Material strength: Made from stainless steel or titanium, the plate provides durable support to withstand the forces on the knee joint during recovery.
• Locking screw technology: It uses locking screws that secure the plate firmly to the bone, reducing the risk of loosening or shifting after surgery.
• Varied sizes: Available in multiple sizes to accommodate different dog breeds and sizes, allowing customized surgical repair.

These features make the Synthes TPLO plate a reliable choice for orthopedic surgeons treating cruciate ligament injuries in dogs.

How Does the Synthes TPLO Plate Work in Surgery?

During a TPLO surgery, the tibial plateau is cut and rotated to change its slope, reducing the strain on the cruciate ligament. The Synthes TPLO plate is then applied to stabilize the bone segments.

The plate holds the bone in the new position while it heals, allowing the dog to regain normal knee function without instability.

• Osteotomy stabilization: The plate bridges the cut bone, maintaining alignment and preventing movement during healing.
• Load distribution: It evenly distributes mechanical forces across the bone to reduce stress concentration and promote bone growth.
• Secure fixation: Locking screws anchor the plate firmly, preventing micromovements that could delay healing or cause implant failure.
• Facilitates early mobility: By stabilizing the joint, the plate allows controlled weight-bearing soon after surgery, aiding recovery.

Proper placement and fixation of the Synthes TPLO plate are critical for surgical success and long-term joint health.

What Are the Benefits of Using Synthes TPLO Plates?

The Synthes TPLO plate offers several advantages over other fixation methods in TPLO surgery. These benefits contribute to improved outcomes and faster recovery for dogs.

Understanding these benefits helps pet owners appreciate why this implant is often recommended by veterinary surgeons.

• Enhanced stability: The plate provides rigid fixation, reducing the risk of postoperative complications like implant loosening or bone displacement.
• Improved healing: Stable fixation promotes faster bone healing and reduces inflammation around the surgical site.
• Reduced pain: By stabilizing the joint, the plate minimizes abnormal joint movement that causes pain during recovery.
• Long-term joint function: Proper alignment and healing help restore normal knee mechanics, reducing the chance of arthritis development.

These benefits make the Synthes TPLO plate a preferred choice for treating cranial cruciate ligament rupture in dogs.

What Are the Surgical Steps for Using a Synthes TPLO Plate?

Successful use of the Synthes TPLO plate requires careful surgical technique. The procedure involves precise bone cutting, plate selection, and screw placement.

Following these steps helps ensure the implant functions correctly and the dog recovers well.

• Preoperative planning: Surgeons measure the tibial plateau and select the appropriate plate size to match the dog's anatomy.
• Performing osteotomy: The tibial plateau is cut using specialized saws to allow rotation and slope adjustment.
• Plate application: The Synthes TPLO plate is positioned on the bone and temporarily fixed with screws to confirm alignment.
• Final fixation: Locking screws are inserted to secure the plate firmly, ensuring stable fixation of the bone segments.

Each step requires precision and experience to minimize complications and optimize healing.

What Are the Postoperative Care Guidelines After Synthes TPLO Plate Surgery?

After surgery, proper care is essential to support healing and prevent implant-related problems. Owners must follow veterinary instructions closely.

Postoperative care focuses on activity restriction, pain management, and monitoring for complications.

• Restricted activity: Limit the dog's movement to prevent stress on the surgical site and allow bone healing.
• Pain control: Administer prescribed analgesics to keep the dog comfortable during recovery.
• Wound monitoring: Check the incision regularly for signs of infection such as redness, swelling, or discharge.
• Follow-up visits: Schedule regular veterinary appointments for X-rays to assess bone healing and implant position.

Adhering to these guidelines improves the chances of a successful outcome and full return to function.

What Are the Potential Complications of Synthes TPLO Plate Use?

While the Synthes TPLO plate is effective, some complications can occur. Awareness of these risks helps owners and surgeons manage them promptly.

Most complications relate to surgical technique, implant issues, or postoperative care.

• Infection risk: Surgical site infections can occur, requiring antibiotics or implant removal in severe cases.
• Implant failure: Plate or screw loosening or breakage may happen if the dog is too active or bone healing is poor.
• Delayed healing: Factors like poor blood supply or infection can slow bone repair, prolonging recovery time.
• Joint stiffness: Inadequate rehabilitation may cause reduced knee mobility and muscle wasting.

Close monitoring and timely intervention reduce the impact of these complications on the dog's recovery.

Conclusion

The Synthes TPLO plate is a key tool in veterinary orthopedic surgery for repairing cruciate ligament injuries in dogs. Its design and locking screw technology provide stable fixation that supports effective bone healing and joint function.

Understanding the plate's use, benefits, and care requirements helps pet owners support their dog's recovery and improve surgical outcomes. With proper surgical technique and postoperative management, the Synthes TPLO plate offers a reliable solution for restoring knee stability and mobility in affected dogs.

FAQs

How long does it take for a dog to heal after TPLO surgery with a Synthes plate?

Healing typically takes 8 to 12 weeks, depending on the dog's size and health. Regular veterinary check-ups monitor bone healing and implant stability during this period.

Can the Synthes TPLO plate be removed after healing?

Plate removal is usually not necessary unless complications arise. Most dogs keep the implant permanently without issues once healing is complete.

Is the Synthes TPLO plate suitable for all dog breeds?

The plate comes in various sizes to fit most breeds, but very small or very large dogs may require customized implants or alternative treatments.

What signs indicate complications after TPLO surgery?

Watch for swelling, redness, discharge, increased pain, or lameness worsening. These signs warrant prompt veterinary evaluation to address possible infection or implant problems.

How soon can a dog bear weight on the leg after Synthes TPLO plate surgery?

Most dogs begin partial weight-bearing within days after surgery, progressing to full weight-bearing over weeks as healing advances under veterinary guidance.

CCL rupture in dogs is not the same injury as ACL rupture in humans.

In humans, the anterior cruciate ligament typically tears during sudden trauma a pivoting fall on a ski slope, a tackle on a football field.

In dogs, the same ligament almost always fails through slow, progressive degeneration that began months or years before the day the dog comes in lame.

Understanding why the canine CCL fails and which dogs are most at risk is essential for prevention strategies and for recognizing early warning signs.

Quick answer: The canine CCL fails through progressive degeneration, not sudden trauma. Key risk factors are breed, obesity, poor fitness, tibial slope, and genetics. At least 50% of dogs that rupture one CCL will rupture the other within 1 to 2 years.

Key takeaways

• CCL rupture results from degeneration, not trauma: ACVS confirms slow, progressive degeneration rather than acute injury to a healthy ligament
• Obesity is the most modifiable risk factor: excess weight increases compressive and shear forces on the CCL with every step
• High-risk breeds include Labrador, Rottweiler, Newfoundland, Mastiff, and Akita: genetic inheritance has been demonstrated in Newfoundlands and Labradors
• Partial tears almost always progress to complete rupture: ACVS confirms this and notes progression is the rule, not the exception
• At least 50% of dogs rupture the opposite CCL within 1 to 2 years of the first rupture
• Neuter status increases CCL risk: spayed and neutered dogs show higher rates in multiple studies

Why dog CCL disease differs from human ACL injury

Colorado State University: "In humans, trauma (such as skiing, football, or soccer injuries) is the most common reason for injury of the ACL.

This 'traumatic' rupture can happen in dogs but is quite rare."

CSU: "Most commonly, CCLD is caused by a combination of many factors, including aging of the ligament (degeneration), obesity, poor physical condition, conformation, and breed."

In humans, a healthy ACL tears from a single high-energy event. In dogs, the ligament is already weakened before it ruptures.

The moment of obvious lameness is the endpoint of a months-long degenerative process.

ACVS: ligament rupture is "the result of subtle, slow degeneration that has been taking place over a period of time rather than the result of sudden trauma to an otherwise healthy ligament."

Fitzpatrick Referrals: "In the vast majority of dogs, the CrCL ruptures as a result of long-term degeneration, whereby the fibres weaken and fray over time, losing their structure and function."

The main causes and risk factors

Degeneration (aging and immune-mediated)

The underlying degenerative process in CCL disease involves progressive breakdown of collagen fibers within the ligament.

PMC (Cranial Cruciate Ligament Rupture Review): "The structural weakening of this joint due to the progressive degeneration of the ligament is the most accredited etiopathogenetic hypothesis."

The degeneration appears to involve both mechanical fatigue and immune-mediated inflammatory processes within the joint.

Synovitis (joint inflammation) often precedes complete rupture and may be detected during veterinary examination before full failure occurs.

Breed and genetics

ACVS: "Certain dog breeds are known to have a higher incidence: Rottweiler, Newfoundland, Staffordshire Terrier, Mastiff, Akita, Saint Bernard, Chesapeake Bay Retriever, and Labrador Retriever."

ACVS: "A genetic mode of inheritance has been shown for Newfoundlands and Labrador Retrievers."

Fitzpatrick Referrals: "Genetic factors are likely very important, with certain breeds being predisposed including Labradors, Rottweilers, Boxers, West Highland White Terriers, and Newfoundlands."

Breeds with low CCL disease incidence include Greyhounds, Dachshunds, Basset Hounds, and Old English Sheepdogs.

Fitzpatrick: "Supporting evidence for a genetic cause was obtained by assessment of family lines and the knowledge that many animals rupture both knees relatively early in life."

Obesity

ACVS: "Poor physical body condition and excessive body weight are risk factors for the development of CrCLD. Both of these factors can be influenced by pet owners."

PMC: "A predisposing factor is obesity, in which the concentrations of circulating inflammatory mediators increase, such as the concentrations of pro-inflammatory adipokines released from adipose tissue, which may contribute to degenerative phenomena."

Obesity matters in two ways: it increases the mechanical load on the CCL with every step, and it elevates systemic inflammation, which accelerates ligament degeneration.

A dog 10% overweight places significantly more stress on both stifle joints with every stride.

Tibial plateau angle (conformation)

The tibial plateau is the top surface of the tibia. In dogs, it slopes caudally. During weight-bearing, this slope creates a cranial shear force on the tibia that the CCL normally resists.

Fitzpatrick: "Increased tibial plateau angle (backwards slope at the top of the tibia) may play a role" in CCL disease.

Dogs with steeper tibial plateau angles experience greater cranial thrust with each step, increasing CCL load.

This is why TPLO and CBLO surgery (which reduce the tibial plateau angle) neutralize the instability rather than replacing the torn ligament.

Neuter status

Multiple studies have found that spayed and neutered dogs have higher rates of CCL disease than intact dogs. The relationship is stronger in some breeds than others.

Proposed mechanisms include the loss of sex hormones that influence joint development and ligament maturation, longer bone growth periods in dogs neutered before skeletal maturity, and altered body composition.

Contralateral (opposite knee) risk

NCBi (Radiographic Risk Factors study): "Among dogs presented with unilateral CCL rupture, a large proportion will develop contralateral CCL rupture within 12 to 24 months of initial diagnosis.

This risk is in the range of 22 to 54% at 6 to 17 months of diagnosis."

CSU: "At least half of the dogs that have a cruciate ligament problem in one knee will likely, at some future time, develop a similar problem in the other knee."

This bilateral risk reflects the systemic nature of CCL degeneration both ligaments are affected by the same genetic, hormonal, and conformation factors.

Partial tears: the warning stage

The CCL typically does not rupture all at once. Partial tears are common and produce intermittent hind limb lameness that owners sometimes attribute to a sprain.

CSU: "Partial tearing of the CCL is common in dogs and frequently precedes complete rupture."

ACVS: "Partial tearing of the CCL is common in dogs and almost always progresses to a full tear over time."

A dog with a partial CCL tear that receives cage rest and returns to activity will almost always eventually progress to complete rupture.

Surgical intervention at the partial tear stage can be considered for active dogs, though evidence on whether it prevents eventual complete rupture is limited.

Signs of CCL disease

• Hind limb lameness, especially after exercise
• Sudden onset of non-weight-bearing on a back leg
• Stiffness when getting up, especially after rest
• Muscle atrophy on the affected hind limb
• Thickening on the inside of the knee joint (medial buttress)
• Positive cranial drawer test or tibial compression test on orthopedic examination

Can CCL tears be prevented?

Risk cannot be eliminated in predisposed breeds, but it can be reduced.

ACVS: "Consistent physical conditioning with regular activity and close monitoring of food intake to maintain a lean body mass is advisable."

Evidence-based prevention strategies:

• Maintain healthy body weight (most impactful modifiable factor)
• Consistent, regular exercise rather than intermittent intense activity
• Avoid sudden load increases (the "weekend warrior" pattern)
• Discuss neutering timing with your vet, particularly in high-risk breeds

For the surgical treatment of CCL rupture, see CBLO surgery in dogs: cost, recovery, and success rate. For the surgery vs. conservative management decision, see canine cruciate injuries: surgery vs. conservative management.

For meniscal injury that often accompanies CCL tears, see torn meniscus surgery cost in dogs. For when CCL disease requires specialist referral, see when to refer for orthopedic surgery.

Frequently asked questions

My dog tore its CCL running in the yard. Wasn't that traumatic?

The event may have looked sudden, but the ligament was almost certainly already degenerated.

ACVS: the rupture is "the result of subtle, slow degeneration... rather than sudden trauma to an otherwise healthy ligament." The yard run was the last straw, not the cause.

Which dog breeds are at highest risk for CCL tears?

ACVS identifies Rottweilers, Newfoundlands, Staffordshire Terriers, Mastiffs, Akitas, Saint Bernards, Chesapeake Bay Retrievers, and Labrador Retrievers as high-incidence breeds. Fitzpatrick Referrals adds Boxers and West Highland White Terriers.

Does obesity really make that much difference?

Yes. Obesity increases both mechanical load on the CCL and systemic inflammation via adipokines from fat tissue.

It is the most modifiable risk factor maintaining healthy body weight is the single most impactful thing an owner can do for CCL disease prevention.

My dog had surgery on one knee. How long before the other goes?

NCBi data: the risk of contralateral CCL rupture is 22 to 54% within 6 to 17 months of the first diagnosis. Monitoring the other knee closely after the first diagnosis is important.

Maintaining lean body weight and avoiding abrupt increases in activity are the main protective strategies.

Can a dog with a partial CCL tear be managed without surgery?

Conservative management (rest, weight loss, physical therapy) may be attempted for partial tears, particularly in small dogs. But ACVS states partial tears "almost always progress to a full tear over time."

Discuss with an orthopedic specialist whether surgery at the partial tear stage is appropriate for your dog.

What is the difference between CCL and ACL?

CCL (cranial cruciate ligament) is the correct term in dogs; ACL (anterior cruciate ligament) is the human equivalent. They are anatomically similar structures that stabilize the knee joint.

The key clinical difference: in humans, ACL tears are usually traumatic; in dogs, CCL tears are almost always degenerative.

Resources

• ACVS. Cranial Cruciate Ligament Disease. acvs.org
• CSU Veterinary Health System. Canine Cruciate Ligament Injury. vetmedbiosci.colostate.edu
• Fitzpatrick Referrals. Cruciate Ligament Disease or Injury. fitzpatrickreferrals.co.uk
• NCBi PMC. Radiographic Risk Factors for Contralateral Rupture in Dogs with Unilateral CCL Rupture. ncbi.nlm.nih.gov
• PMC. Cranial Cruciate Ligament Rupture in Dogs: Review on Biomechanics, Etiopathogenetic Factors and Rehabilitation. ncbi.nlm.nih.gov