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Preparing for Your Dog’s TPLO Surgery

Preparing for Your Dog’s TPLO Surgery

TPLO

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Owners

Discover simple, stress-free ways to prepare your dog for TPLO surgery. Practical tips for a safe procedure and smooth recovery at home

By 

Sustainable Vet Group

Updated on

August 13, 2026

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This article is for informational purposes only and is not a substitute for professional veterinary advice. Every case is unique, so always consult your veterinarian for guidance specific to your pet.

This content is intended for veterinary professionals for educational purposes. It does not replace clinical judgment or tailored advice. Always rely on your training, expertise, and the specific context of your patients.

Preparing for Your Dog’s TPLO Surgery

The better prepared you are before your dog's TPLO surgery, the smoother the procedure and the early recovery will be.

Preparation covers two distinct areas: medical preparation managed with your vet in the days and weeks before surgery, and home preparation completed before your dog comes home.

Both matter and both require specific actions.

 

Quick answer: Key TPLO surgery preparation steps: complete pre-surgical bloodwork; adjust or discontinue medications as directed; fast the dog 8 to 12 hours before surgery; set up the crate, non-slip mats, and e-collar before surgery day; fill prescriptions in advance; brief all household members.

 

Key takeaways

  • Pre-surgical bloodwork is standard: a CBC and blood chemistry panel confirm the dog can safely handle anesthesia; senior dogs or those with health conditions may need additional testing
  • Fasting is non-negotiable: dogs are fasted the night before surgery to prevent anesthetic complications; typically 8 to 12 hours; follow your vet's specific instructions
  • Some medications must be stopped before surgery: NSAIDs, certain supplements, and other drugs can increase bleeding or interfere with anesthesia; discuss all medications with your vet at least 1 week before
  • The recovery space must be ready before the dog comes home: have the crate, non-slip mats, and supplies in place before surgery day
  • Post-surgical medications must be filled before surgery day: NSAID prescriptions and gabapentin should be ready when the dog arrives home
  • Household members including children need briefing: educate children about activity restrictions before surgery so they do not inadvertently excite or disturb the recovering dog

Medical preparation: weeks before surgery

Pre-surgical health assessment

Your vet or the surgical team will schedule a pre-surgical examination. This typically includes:

Physical examination: auscultation (heart and lungs), body weight assessment (obesity increases anesthetic and surgical risk), orthopedic examination of the affected limb, and general health screening.

Pre-surgical bloodwork: SustainableVet.org confirms that pre-surgery blood tests usually include a complete blood count and blood chemistry panel to check for anemia, kidney or liver problems, and signs of infection; these tests confirm organs can safely handle anesthesia and healing.

Additional testing for senior or compromised dogs: dogs over 7 to 8 years, those with known health conditions, or those with abnormal screening results may need urinalysis, chest radiographs (to assess cardiac and pulmonary health), or electrocardiography. Cainhoy Vet confirms: for senior pets or those with underlying conditions, additional diagnostics such as X-rays or ECGs may be recommended.

Weight management before surgery

If your dog is overweight, weight reduction before TPLO reduces surgical and anesthetic risk. Midvalley Animal Clinic confirms: increased weight exerts more stress on implants and is an additional hurdle to recovery.

If your vet identifies obesity as a concern, follow their dietary guidance in the weeks leading up to surgery.

Medication review and adjustment

At the pre-surgical consultation, provide a complete list of all medications, supplements, and herbal products the dog is currently taking.

SustainableVet.org confirms: some medications, such as NSAIDs or steroids, may need to be paused before the procedure.

Typical medication guidance:

  • NSAIDs (carprofen, meloxicam, aspirin, ibuprofen): typically stopped 5 to 7 days before surgery to reduce bleeding risk
  • Steroids (prednisone, prednisolone): typically stopped 5 to 14 days before surgery
  • Fish oil and some supplements: may be stopped 1 week before surgery
  • Gabapentin and opioids: usually continued as directed

Never stop a prescribed medication without explicit vet instruction.

Pre-surgical bathing

Virginia Vet Centers confirms: your vet may recommend bathing before surgery if you wish, since post-surgical wound care restricts bathing for 10 to 14 days.

Give a bath 1 to 2 days before surgery -- close enough to reduce skin bacteria counts while allowing full drying.

Fasting instructions: the night before surgery

Fasting prevents regurgitation and aspiration of stomach contents under anesthesia -- a potentially fatal complication.

Highlands Vet Hospital confirms: most dogs should stop eating 8 to 12 hours before surgery; always follow your vet's specific instructions.

Standard guidance:

  • No food from approximately 10 PM the night before a morning surgery
  • Water: rules vary by facility; many allow water until midnight or 6 hours before surgery; follow your vet's specific instructions
  • Medications on the morning of surgery: ask your vet specifically which medications (if any) can be given with a very small amount of food or water on the surgery morning

Home preparation: before surgery day

Setting up the recovery space

SustainableVet.org confirms: before your dog comes home, prepare a safe, quiet recovery space with a crate or small room, soft bedding, good airflow, and away from stairs or slippery floors.

Recovery space checklist:

  • Crate (sized correctly: stand, turn, lie; not pace) or X-pen in place
  • Non-slip mats or yoga mats covering all hard flooring in the recovery area
  • Soft, washable bedding inside the crate
  • Water bowl accessible at ground level
  • Food bowl accessible at ground level
  • Baby gates blocking stairs, kitchen, and any rooms the dog should not access
  • Furniture blocked or inaccessible to prevent jumping

TPLO Info confirms: you can invest in a gate or large crate to limit movement; educate children in the household as much as possible about the pet's surgery ahead of time.

Supplies to have ready before surgery

Essential:

  • E-collar (typically provided by the surgical facility, but confirm in advance)
  • Ice pack or bag of frozen peas (cold therapy for the first 3 to 5 days)
  • Sling or towel harness for helping the dog rise and walk (for large dogs)
  • Leash (4 to 6 foot, not retractable) for all outdoor trips

Nice to have:

  • Food puzzle or lick mat (for mental stimulation during confinement)
  • Frozen Kong treats prepared and in freezer
  • Dog ramp or steps for the car (to load and unload without jumping)

Maplewood Vet confirms: having the right supplies ready before surgery day can help reduce stress and ensure your pet's transition home is as comfortable as possible.

Medication pickup

Prescriptions for post-surgical pain management (NSAIDs, gabapentin) are typically sent to a pharmacy before surgery or dispensed at discharge.

Confirm with your surgical team whether prescriptions need to be filled before surgery day -- this prevents a scramble on discharge day when the dog is in pain and waiting.

Surgery day: what to bring and expect

What to bring:

  • Your dog (fasted, no food since the designated cutoff)
  • Prior medical records if visiting a new facility (vaccination records, prior bloodwork, medication list)
  • The e-collar if provided in advance
  • Your contact phone number -- the team will call you during and after surgery

What to expect:

  • Drop-off: typically early morning; the dog is admitted, weighed, examined, and IV catheter placed
  • Surgery duration: typically 1.5 to 2 hours for TPLO
  • Post-surgical hospitalization: most dogs stay overnight; some facilities discharge same day
  • Discharge call: your vet will call to update you on how surgery went before discharge

Virginia Vet Centers confirms: most dogs stay at the hospital overnight after TPLO surgery; the veterinary team will provide detailed discharge instructions explaining medications, activity restrictions, wound care, and rehabilitation.

Discharge: what to review before leaving the hospital

At discharge, review:

  1. Medication schedule (when, how, with or without food)
  2. Wound care instructions (what to look for, how to manage)
  3. Activity restrictions (what is and is not allowed)
  4. Signs that require a call to the vet
  5. Schedule of follow-up appointments (2-week recheck, 6-week radiograph)

For the full recovery guide, see what to expect after TPLO surgery in dogs. For confinement setup, see how to confine your dog after TPLO surgery.

For keeping your dog calm, see how to keep a dog calm after TPLO surgery. For infection prevention, see how can TPLO infections be prevented post-operatively?.

Frequently asked questions

What happens if my dog ate something before surgery?

Call your surgical team immediately. Even a small amount of food can increase anesthetic risk. In most cases the surgery will be rescheduled. Do not wait until surgery day to inform them.

Can I give my dog medications the morning of surgery?

Ask your vet specifically about each medication. Some (like thyroid medications) should be given; others (like NSAIDs) should not. Never assume -- confirm before surgery day.

How do I transport my dog home from surgery?

Line the car with clean towels or a mat. Bring a helper if possible -- one person drives, one sits with the dog.

For large dogs, use a sling or lifting harness to assist getting in and out of the car. Do not let the dog jump in or out of the vehicle.

How long after surgery before I can leave my dog alone?

The first 24 to 48 hours are the highest-risk period. If possible, arrange for someone to be with the dog for the first day and night at home.

After 48 hours, crated dogs can be left alone for reasonable durations (up to 4 to 6 hours). Never leave the dog unsupervised without confinement.

Do I need to prepare other pets in the household?

Keep other pets separated from the recovering dog for at least the first 2 weeks. Excited greetings from other dogs can cause the TPLO dog to jump or spin.

Have a plan for where other pets will be confined when the recovering dog is out of the crate.

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Step #1

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Ensuring a clean surgical field starts with proper skin preparation. This video demonstrates the best practices for:

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