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Types of Cysts and Tumors in Dogs

Types of Cysts and Tumors in Dogs

General Tips

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Owners

Explore the common types of cysts and tumors in dogs, their signs, diagnosis, and treatment options for better pet care.

By 

Sustainable Vet Group

Updated on

August 13, 2026

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This article is for informational purposes only and is not a substitute for professional veterinary advice. Every case is unique, so always consult your veterinarian for guidance specific to your pet.

This content is intended for veterinary professionals for educational purposes. It does not replace clinical judgment or tailored advice. Always rely on your training, expertise, and the specific context of your patients.

Types of Cysts and Tumors in Dogs

Finding a lump on your dog is one of the most common reasons owners call their vet. Most lumps in dogs are benign but some are not, and it is not possible to reliably tell the difference by looking or feeling alone.

This guide covers every common type of cyst and tumor in dogs: what each one looks like, where it tends to appear, and which ones require prompt attention.

 

Quick answer: Dogs develop cysts (almost always benign) and tumors (benign or malignant). Common benign types include lipomas and sebaceous cysts. Mast cell tumors are the most common malignant skin tumor. All new lumps need vet assessment.

 

Key takeaways

  • Cysts are almost always benign and consist of a sac filled with fluid, sebum, or cellular material
  • Tumors can be benign or malignant; appearance and feel alone cannot reliably distinguish between them
  • Lipomas are the most common benign tumor in dogs: soft, movable fatty lumps most often found in middle-aged to senior dogs
  • Mast cell tumors are the most common malignant skin tumor in dogs, representing 11% of all canine skin cancers
  • Fine needle aspiration (FNA) is the standard first diagnostic step for any unidentified lump it is quick, minimally invasive, and usually provides a definitive answer
  • Any lump that grows rapidly, ulcerates, bleeds, or causes pain needs same-day veterinary evaluation

Cysts vs. tumors: the key distinction

A cyst is a sac-like structure with a defined wall, filled with liquid or semi-solid material. Dr. Buzby's ToeGrips explains the distinction clearly: cysts "are masses made up of a cavity that contains liquid or semi-solid material," while "tumors, whether benign or malignant, are comprised of solid tissue that forms from abnormal cell growth."

This matters for two reasons:

  1. Cysts are not cancerous and do not spread to other parts of the body
  2. Tumors vary widely a lipoma (benign fat tumor) behaves very differently from a mast cell tumor (potentially malignant)

The challenge: some malignant tumors feel soft and movable, while some benign cysts feel firm. Merck Veterinary Manual warns specifically about mast cell tumors: "These tumors vary greatly in size and rate of growth. They can mimic lipomas; therefore, visual signs alone cannot establish a diagnosis."

Common types of cysts in dogs

1. Sebaceous cysts

Formed when the opening of a sebaceous (oil) gland becomes blocked, trapping sebum inside. PetMD describes them as containing a thick material that releases "white, yellow, or brown" discharge when expressed.

  • Appearance: raised bump, often with a whitish or bluish tint through the skin
  • Location: anywhere on the body, but most common on the trunk, head, and limbs
  • Size: usually small (under 1 cm) but can grow larger
  • Behavior: slow-growing; may rupture and release pasty discharge; prone to secondary infection if ruptured
  • Treatment: monitoring for small, stable cysts; surgical removal if infected, growing, or bothering the dog
  • Important: Merck cautions against squeezing: "You should not attempt to remove the cysts by squeezing them because this can spread the cyst contents into the surrounding tissues."

2. Follicular cysts (epidermoid cysts)

Associated with hair follicles rather than sebaceous glands. PetMD: "Follicular cysts are large, benign bumps on the skin that grow up from the hair follicle. They may release a thick material that is white, yellow, or brown when you push on them."

  • Appearance: firm, raised bump; contents are often dark, cheesy, or foul-smelling when expressed
  • Location: anywhere, but legs and around the mouth are particularly common according to Bark & Whiskers
  • Behavior: may become infected (folliculitis); can grow to several centimeters and become painful
  • Treatment: monitoring if stable; surgical removal if growing, infected, or painful; will not regrow if fully removed

A specific subtype interdigital cysts forms between the toes. Dr. Buzby's ToeGrips explains: "These cysts develop between the toes and are often a consequence of allergies, obesity, or breed-related factors. The affected hair follicle becomes inflamed and may rupture."

3. True cysts (sweat gland cysts)

Form in the secretory lining of sweat glands, which continuously produces fluid the more fluid produced, the larger the cyst grows. True cysts are most common around the eyes and in the ear canals.

  • Appearance: smooth, fluid-filled, usually bluish or translucent
  • Location: eyelids, ear canals most commonly
  • Behavior: slow-growing, almost always benign; can impair vision if near the eye
  • Treatment: surgical removal or laser ablation if causing problems

4. Dermoid cysts

Congenital cysts that form when a piece of epidermis becomes trapped below the skin during fetal development. Merck notes they are "most commonly found in Boxers, Kerry Blue Terriers, and Rhodesian Ridgebacks. Most dermoid cysts are multiple and contain fully formed hair shafts."

  • Appearance: firm, often contains hair
  • Behavior: benign; can become infected
  • Treatment: surgical removal is the definitive treatment

Common types of benign tumors in dogs

5. Lipoma (fatty tumor)

University of Illinois veterinary cytology department confirms: "Lipomas are a benign mesenchymal tumor and probably the most common benign tumor in dogs."

  • Appearance: soft, round, movable under the skin; no overlying hair changes
  • Location: trunk and upper limbs most common; can occur anywhere
  • At-risk dogs: older and overweight dogs
  • Behavior: slow-growing; most remain stable for years; do not spread or become malignant
  • Treatment: monitoring is standard for most; surgical removal if the lipoma is in a location causing discomfort (over a joint, in the axilla, on the leg where it affects movement)

The exception is the infiltrative lipoma, which grows into surrounding muscle and fascia rather than displacing it. These require more aggressive surgical removal.

6. Histiocytoma

A benign skin tumor arising from immune (Langerhans) cells in the skin. PetMD describes them as tumors that "usually regress spontaneously over time without treatment."

  • Appearance: small, round, firm, raised, often red ("button-like") on the surface; may ulcerate
  • Location: most common on the head, ears, and limbs
  • At-risk dogs: young dogs under 3 years; Boxers, Bulldogs, Dachshunds, Cocker Spaniels
  • Behavior: hallmark feature is spontaneous regression within 1 to 3 months
  • Treatment: monitoring most resolve without treatment; removal if the dog is bothering it or if it persists beyond 3 months

7. Skin tags (acrochordons)

Fleshy, pedunculated (on a stalk) growths that form where skin rubs together. Bark & Whiskers: "These are small, fleshy growths that often appear on areas where the skin rubs together, like the armpit or eyelids. They're usually harmless unless they get irritated."

  • Treatment: none required unless causing irritation; simple surgical removal

8. Papillomas (warts)

Caused by the canine papillomavirus. Embrace Pet Insurance: "These are caused by a virus and are most often found in and around the mouth of young dogs."

  • Appearance: cauliflower-like, pale, rough surface; clustered
  • Location: mouth, lips, eyelids
  • At-risk dogs: young dogs with immature immunity; immunosuppressed dogs
  • Behavior: contagious between dogs; most resolve spontaneously within weeks to months
  • Treatment: monitoring; antiviral treatment or surgical removal for persistent or symptomatic cases

Mast cell tumors: the most important malignant skin tumor

Mast cell tumors (MCTs) deserve special attention. The published consensus review in PMC confirms: "It is the most common malignant skin tumor in dogs, corresponding to 11% of skin cancer cases."

Why they are important:

  • They are highly variable in appearance they can look like almost anything: a small firm nodule, a soft squishy mass, an ulcerated sore, or a wart
  • They can change size rapidly (especially when stimulated by pressure or trauma), which is a characteristic feature called Darier's sign
  • They release histamine and other chemicals, which can cause local redness and swelling

At-risk breeds: Merck Veterinary Manual identifies Boxers and Pugs (often multiple tumors), Rhodesian Ridgebacks, and Boston Terriers as especially prone.

High-risk locations: Merck: "Tumors located near mucous membranes, feet, prepuce, or on the lower surface of the body are more likely to spread than mast cell tumors in other areas."

Diagnosis: fine needle aspiration. Mast cells have a characteristic granular appearance under the microscope that is usually immediately identifiable.

Treatment: surgical removal with wide margins; grade determines whether additional treatment (chemotherapy, radiation) is needed.

For how to assess whether a lump should be removed, see how to tell which lumps need removal. For mast cell tumor removal cost specifically, see mast cell tumor as a common tumor type.

Other significant tumor types

Melanoma

Arises from pigment-producing cells. Bark & Whiskers notes that "some types can be aggressive." Oral melanomas (in the mouth) are significantly more aggressive than cutaneous (skin) melanomas. A dark, irregularly shaped growth on or around the mouth, on the nail bed, or on mucosal surfaces warrants prompt evaluation.

Perianal adenoma

PetMD: "Perianal adenomas are benign growths common in older, unneutered male dogs. They grow from oil glands near the anus but can also occur in similar glands along the abdomen, on the back, and near the tail." Neutering is both preventive and may cause regression of existing tumors.

How vets diagnose lumps: fine needle aspiration

FNA is the standard first step for any unidentified lump. A thin needle is inserted into the mass and cells are aspirated onto a slide for microscopic examination. University of Illinois veterinary cytology: this technique reliably distinguishes lipomas, cysts, mast cell tumors, and histiocytomas in most cases.

FNA is quick, minimally invasive, and can be done in a routine vet visit without anesthesia for most lumps. If FNA is inconclusive, a biopsy (removing a small tissue core) or surgical excision with histopathology provides a definitive diagnosis.

For when cysts and tumors require surgery based on diagnosis, see when cysts and tumors require surgery. For how red lumps on the leg relate to these growth types, see red lumps as a presenting sign of cysts or tumors.

When to call the vet immediately

Contact your vet the same day if a lump:

  • Appeared suddenly and is growing fast
  • Is ulcerated, bleeding, or has discharge
  • Is warm and painful to the touch
  • Changes size rapidly (getting larger then smaller mast cell feature)
  • Is on a high-risk location: mouth, nail bed, foot pad, groin
  • Causes your dog pain or changes their behavior

For cost context on tumor removal, see cost of removing tumors.

Frequently asked questions

Can I tell if a lump is cancerous by touching it?

No. Merck Veterinary Manual is explicit that mast cell tumors "can mimic lipomas; therefore, visual signs alone cannot establish a diagnosis." Soft, movable lumps can be malignant; firm, fixed lumps can be benign. Fine needle aspiration by a vet is the only reliable way to get an answer.

Should I wait and watch a new lump on my dog?

For lumps that are small, stable, and have been present without change for months, monitoring is reasonable. Any new lump should be evaluated by a vet within a few weeks of discovery not because every lump is dangerous, but because knowing what it is guides whether monitoring or action is appropriate.

How often do dogs get cancer?

Cancer is the leading cause of death in dogs over 10 years of age. However, many lumps found on dogs are benign. The probability of malignancy increases with age, rapid growth, ulceration, and location on or near mucous membranes.

What is fine needle aspiration and does it hurt?

FNA involves inserting a thin needle into the lump to collect a small sample of cells. Most dogs tolerate it without sedation and show little reaction. It takes a few seconds and provides very useful diagnostic information. It is much less invasive than a biopsy.

My dog has multiple lipomas. Is that a concern?

Multiple lipomas are common in older dogs, especially Labrador Retrievers and overweight dogs. Most are benign and can be monitored. Your vet will recommend FNA for any new or atypical lump in a dog with known lipomas to make sure a new growth is not a different tumor type that happens to look similar.

What is the difference between a cyst and an abscess?

Both are fluid-filled pockets but with different contents and causes. A cyst contains sebum, cellular debris, or glandular secretions and is usually not infected. An abscess contains pus the product of bacterial infection and is almost always painful, warm, and surrounded by inflamed tissue. Abscesses need antibiotic treatment; many cysts can simply be monitored.

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