TPLO (Tibial Plateau Leveling Osteotomy) surgery is a common procedure to stabilize a dog's knee after a cranial cruciate ligament (CCL) rupture. It involves cutting and repositioning the tibia to reduce strain on the ligament, allowing for better joint function. Like any surgery, TPLO has a risk of complications, with incision infections being a primary concern.

Infections can happen due to bacterial contamination during surgery, improper post-op care, excessive licking or chewing of the incision, or underlying conditions like diabetes or a weakened immune system. Signs of infection include redness, swelling, warmth, discharge, and delayed healing.

The risk of infection after TPLO is relatively low, occurring in about 3-10% of cases. Factors like surgical technique, sterile conditions, and strict post-operative management greatly affect the outcome. Early detection and quick treatment with antibiotics and wound care are crucial to prevent complications and ensure a successful recovery.

Symptoms and Warning Signs of TPLO Incision Infection

Recognizing the symptoms of an infection early is crucial for preventing complications after TPLO (Tibial Plateau Leveling Osteotomy) surgery. Infections can range from mild to severe, potentially affecting healing and the long-term success of the procedure. Understanding the difference between early and advanced signs can help ensure timely intervention.

Early Signs of Infection

In the initial stages, an infection may present with mild symptoms that can sometimes be mistaken for normal healing. These include:

• Redness and swelling around the incision site, which may be slightly warm to the touch.
• Mild pain or tenderness, which persists beyond the expected post-surgical discomfort.
• Clear or slightly yellow discharge, which may indicate the presence of bacteria.

If detected at this stage, infections are often manageable with topical treatments, antibiotics, and proper wound care.

Advanced Signs of Infection

As an infection worsens, more severe symptoms may develop, indicating deeper tissue involvement and potential systemic infection. These include:

• Thick, pus-like discharge from the incision, often accompanied by a foul odor.
• Significant swelling and warmth, which may extend beyond the incision area.
• Fever and lethargy, as the body mounts an immune response.
• Increased lameness or reluctance to bear weight, signaling pain or joint involvement.

Advanced infections require urgent veterinary care, as untreated cases can lead to delayed healing, implant complications, or systemic illness. Immediate intervention, such as antibiotics, wound debridement, or even surgical revision, may be necessary.

Monitoring the incision closely in the weeks following TPLO surgery is essential. Any changes in the wound’s appearance, excessive discomfort, or behavioral changes in your dog should be reported to a veterinarian promptly to prevent complications.

Causes of TPLO Incision Infection

A TPLO (Tibial Plateau Leveling Osteotomy) incision infection can occur due to various factors, either during the surgery or in the post-operative recovery period. Identifying and minimizing these risks is essential for ensuring a smooth healing process.

Bacterial Contamination During or After Surgery

Despite strict sterile protocols, bacteria can sometimes enter the surgical site during the procedure. This can happen due to contamination from the skin, surgical instruments, or even the surrounding environment. Post-operatively, improper wound care or exposure to unclean surfaces can introduce bacteria, increasing infection risk.

Poor Post-Op Wound Care

Proper post-operative care is critical to prevent infection. Failure to keep the incision clean and dry, skipping prescribed antibiotics, or neglecting follow-up visits can allow bacteria to proliferate. Owners must follow all veterinary instructions carefully, including cleaning protocols and medication administration.

Licking or Chewing the Incision Site

Dogs instinctively lick their wounds, which can introduce bacteria from their mouths into the incision. Excessive licking or chewing can also cause trauma to the site, delaying healing. The use of an Elizabethan collar (E-collar) or medical pet shirt is essential to prevent self-inflicted wound contamination.

Moisture Buildup Around the Incision

A damp environment around the incision can promote bacterial growth. Moisture can accumulate from bathing, wet bedding, or excessive sweating, making it essential to keep the area dry until fully healed.

Underlying Health Conditions

Dogs with pre-existing conditions such as diabetes, Cushing’s disease, or immune disorders have a higher risk of infection due to impaired wound healing. Such cases require extra vigilance in monitoring for signs of infection.

Implants and Their Role in Infection Risk

The metal implants used in TPLO surgery can serve as a surface for bacterial adhesion. If bacteria form a biofilm on the implant, it can lead to a deep-seated infection that may require implant removal or surgical revision.

To minimize this risk, many surgeons use Simini Protect Lavage, a non-antibiotic surgical lavage designed to reduce bacterial contamination and prevent biofilm formation. Unlike traditional solutions, Simini Protect Lavage actively disrupts bacterial adhesion, helping to lower infection risks without contributing to antibiotic resistance. Its use in TPLO and other orthopedic procedures has shown promising results in enhancing post-surgical outcomes.

Preventing infection requires a combination of strict surgical protocols, diligent post-op care, and close monitoring of the incision site for any signs of complications.

How TPLO Infections Are Diagnosed

Diagnosing a TPLO incision infection requires a thorough evaluation by a veterinarian to determine the severity and appropriate treatment plan. Early detection is key to preventing complications such as delayed healing, deep tissue infections, or implant failure.

Physical Examination

The first step in diagnosing an infection is a detailed physical examination of the incision site. The veterinarian will check for common signs of infection, including:

• Redness and swelling around the incision.
• Abnormal discharge (pus, thick yellow fluid, or foul-smelling secretions).
• Increased warmth in the surrounding tissue.
• Pain response when the area is gently palpated.
• Signs of systemic illness, such as fever or lethargy.

Diagnostic Tests

If an infection is suspected, further diagnostic tests help confirm the presence and extent of the infection.

• Wound Culture and Sensitivity Test - A swab of the incision site is collected to identify the specific bacterial strain causing the infection. This helps determine the most effective antibiotic treatment.
• Complete Blood Count (CBC) - Blood tests check for elevated white blood cell counts (WBCs), which indicate an immune response to infection. Other markers, such as increased neutrophils, may suggest a bacterial infection.
• X-rays or Advanced Imaging - If the infection has progressed or involves the surgical implants, X-rays or ultrasound imaging may be used to assess deep tissue involvement. In some cases, an infection can lead to osteomyelitis (bone infection) or implant loosening, requiring further surgical intervention.

Prompt and accurate diagnosis ensures that treatment is initiated quickly, reducing the risk of complications and improving the chances of a full recovery.

Potential Complications of an Untreated TPLO Incision Infection

If a TPLO incision infection is left untreated, it can lead to serious complications that may jeopardize the success of the surgery and the dog’s long-term mobility. Early intervention is crucial to prevent these risks.

Implant Failure and the Need for Removal or Revision Surgery

TPLO surgery involves the placement of metal implants (plates and screws) to stabilize the tibia. If bacteria colonize the implant, they can form a biofilm, making the infection difficult to treat with antibiotics alone. This can lead to implant loosening or failure, requiring removal or revision surgery to replace the affected hardware. A second surgery increases recovery time and risk of further complications.

Read more about - Signs of TPLO Failure in Dogs & When to See a Vet

Deep Bone Infection (Osteomyelitis)

When an infection spreads beyond the incision site into the bone tissue, it can cause osteomyelitis, a severe and persistent infection. Bone infections are challenging to treat and often require long-term antibiotics, surgical debridement, or even partial bone removal in extreme cases. Osteomyelitis can significantly delay healing and may compromise limb function.

Delayed Healing, Prolonged Pain, and Lameness

An untreated infection slows down wound healing, leading to persistent inflammation, chronic pain, and prolonged lameness. Infections interfere with the body’s natural healing process, increasing the risk of poor scar formation and weakening the stability of the joint. This can result in long-term mobility issues, affecting the dog’s quality of life.

Risk of Systemic Infection (Sepsis)

If bacteria enter the bloodstream, the infection can become systemic, leading to sepsis, a life-threatening condition. Sepsis causes widespread inflammation, organ dysfunction, and severe illness. Immediate hospitalization, intravenous antibiotics, and aggressive supportive care are required in such cases.

Preventing complications requires early diagnosis, strict post-op care, and immediate treatment of any signs of infection to ensure a smooth recovery.

Treatment Options for TPLO Incision Infections

A TPLO incision infection requires prompt and appropriate treatment to prevent complications and ensure proper healing. The treatment plan depends on the severity of the infection, the presence of bacterial colonization on the implants, and the dog’s overall health.

Antibiotic Therapy

Antibiotics are the first line of treatment for a TPLO incision infection. The choice of antibiotic depends on wound culture and sensitivity testing, ensuring effective targeting of the bacteria.

• Oral antibiotics (e.g., cephalexin, clindamycin, or enrofloxacin) are commonly prescribed for mild to moderate infections.
• Topical antibiotics (e.g., silver sulfadiazine or mupirocin) may be used to manage surface-level infections.
• If the infection is deep-seated or spreading, intravenous (IV) antibiotics may be required for better systemic control.

Wound Cleaning and Care

Proper wound care helps clear bacteria and promote healing. This includes:

• Cleaning the incision with veterinary-approved antiseptic solutions (chlorhexidine or diluted povidone-iodine).
• Avoiding excessive moisture buildup around the wound.
• Preventing licking or chewing with an Elizabethan collar (E-collar) or medical pet shirt.
• Ensuring the bandage (if used) is clean and changed as recommended by the veterinarian.

Pain Management

Infections cause inflammation and discomfort, so pain relief is an important part of treatment.

• Non-steroidal anti-inflammatory drugs (NSAIDs) such as carprofen or meloxicam may be prescribed to reduce pain and swelling.
• If severe discomfort persists, stronger pain relievers may be necessary.

Surgical Intervention

For infections that do not respond to antibiotics or involve the implants, surgical intervention may be needed:

• Flushing and debridement – The vet may clean and remove infected tissue under anesthesia to prevent further bacterial spread.
• Implant removal or revision – If bacteria have colonized the TPLO plate and screws, implant removal may be necessary, followed by a prolonged course of antibiotics to clear the infection.

Timely and appropriate treatment is essential to prevent long-term complications and ensure a smooth recovery. Close veterinary supervision and adherence to post-op care instructions significantly improve outcomes.

When to Call Your Veterinarian

Recognizing the signs of a TPLO incision infection early and seeking veterinary care promptly can prevent serious complications. Certain symptoms indicate the need for immediate medical attention:

• Excessive swelling, redness, or warmth around the incision.
• Thick, pus-like discharge or a foul odor from the wound.
• Persistent pain or worsening lameness beyond the expected healing period.
• Fever, lethargy, or loss of appetite, which may indicate a systemic infection.
• Sudden changes in behavior, such as reluctance to move or increased sensitivity around the incision.

How Quickly Should an Infection Be Addressed?

If you notice any signs of infection, contact your veterinarian immediately. Mild infections caught early may be treated with antibiotics and wound care, but delays in treatment can lead to deeper infections, increasing the risk of implant failure or systemic illness.

What to Expect During a Vet Visit

Your veterinarian will:

• Perform a physical examination of the incision.
• Conduct diagnostic tests (wound cultures, blood tests, or X-rays) if needed.
• Prescribe antibiotics or pain medication based on the infection’s severity.
• Recommend wound cleaning protocols or, in severe cases, surgical intervention to remove infected tissue or implants.

Prompt veterinary care ensures a smoother recovery and reduces the risk of long-term complications.

Preventing TPLO Incision Infections

Preventing infection after TPLO surgery is crucial for ensuring a smooth recovery and avoiding complications. Proper post-operative care significantly reduces the risk of infection and promotes faster healing.

Proper At-Home Wound Care Routine

A clean and well-maintained incision site is essential for preventing bacterial growth. Follow these steps to ensure proper wound care:

• Inspect the incision daily for redness, swelling, or discharge.
• Use vet-approved antiseptic solutions if cleaning is necessary.
• Avoid touching the wound with unclean hands to prevent contamination.
• Follow the prescribed antibiotic regimen to eliminate any potential bacterial infections.

Importance of E-Collars to Prevent Licking

Dogs instinctively lick wounds, but their mouths contain bacteria that can introduce infection.

• An Elizabethan collar (E-collar) or medical pet shirt should be used at all times until the incision fully heals.
• Even brief periods of licking can introduce bacteria, delaying healing and increasing infection risk.

Keeping the Incision Dry and Clean

Moisture creates an ideal environment for bacterial growth, so it’s important to:

• Prevent the incision from getting wet—no bathing or swimming until cleared by the vet.
• Keep the bedding clean and dry to avoid contamination.
• If the incision gets wet, gently pat it dry with a clean, soft cloth.

Following Post-Op Care Instructions Strictly

Veterinary post-op guidelines should be followed precisely, including:

• Restricted activity to prevent excessive movement that could stress the incision.
• Proper medication schedules, including antibiotics and pain relievers.
• Scheduled follow-up visits to monitor healing progress.

Monitoring for Any Early Signs of Infection

Even with proper care, infections can still develop. Watch for:

• Redness, swelling, or discharge from the incision.
• Excessive licking or signs of discomfort around the area.
• Changes in behavior, such as lethargy or reluctance to move.

By taking proactive steps in at-home care, pet owners can significantly reduce the chances of post-operative infections and support a successful TPLO recovery.

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Read more about:

• TPLO Failure Symptoms
• TPLO Surgery Cost Guide
• Long-Term Outcomes of TPLO Surgery
• Common Causes of Limping in Dogs Post-TPLO Surgery

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Conclusion

A TPLO incision infection can slow down healing and cause serious problems if not treated. It's important to notice early signs of infection, like redness, swelling, discharge, or increased pain, to prevent further issues. Quick veterinary care can greatly improve recovery results.

Proper post-operative wound care, such as keeping the incision clean and dry, using an E-collar to prevent licking, and following all prescribed medications, helps reduce the risk of infection. Watching for any changes in the incision site or behavior allows for early action if needed.

If an infection happens, quick diagnosis and treatment with antibiotics, wound care, or surgery ensure the best recovery possible. By being watchful and proactive in post-op care, pet owners can support a smooth healing process and help their dog regain mobility safely.

FAQs

How do I know if my TPLO incision is infected?

A TPLO incision infection may show signs such as redness, swelling, warmth, and abnormal discharge (yellow, pus-like, or foul-smelling fluid). The incision may become painful, and your dog might show increased licking, lethargy, fever, or reluctance to walk. If you notice any of these symptoms, contact your veterinarian immediately for evaluation and treatment.

How do you treat a TPLO infection?

Treatment depends on the severity of the infection. Mild cases may be managed with oral antibiotics and wound cleaning, while severe infections might require intravenous antibiotics, wound flushing, or even implant removal if bacteria form a biofilm. Pain management and restricted movement are also essential for recovery. Early treatment ensures the best outcomes and prevents complications like deep bone infections or implant failure.

What to do if my dog's incision is infected?

If you suspect an infection, contact your veterinarian immediately. Avoid cleaning the wound with unapproved solutions, and prevent your dog from licking the incision by using an E-collar or protective covering. The vet may prescribe antibiotics, pain relief, or wound debridement depending on the infection's severity. Delaying treatment can worsen the infection and lead to complications.

How common is infection after TPLO surgery?

Infections after TPLO surgery are relatively uncommon, occurring in about 3-10% of cases. The risk increases with factors like poor post-op care, excessive licking, moisture exposure, or underlying health issues such as diabetes or immune suppression. Following strict wound care protocols and monitoring for early signs of infection significantly reduces the risk.

What is the infection rate for TPLO?

The infection rate for TPLO surgery ranges from 3-10%, depending on factors such as surgical technique, sterility, and post-operative care. Using advanced infection prevention methods, such as Simini Protect Lavage, proper antibiotic use, and strict wound monitoring, can help minimize infection risks. Prompt intervention at the first sign of infection is essential.

What does the start of an infected incision look like?

The early signs of an infected TPLO incision include increased redness, mild swelling, warmth, and clear to yellow discharge. The area may become more painful than expected during normal healing, and your dog may lick or chew the incision excessively. If left untreated, symptoms can worsen, leading to pus formation, odor, and systemic illness. Any suspicious changes should be evaluated by a veterinarian immediately.

TPLO (Tibial Plateau Leveling Osteotomy) is a common surgery used to treat cranial cruciate ligament (CCL) injuries in dogs. It involves cutting and repositioning the tibia to stabilize the knee joint, reducing the need for the damaged ligament. Although TPLO has a high success rate, complications can still occur even with proper surgical technique.

Complications can arise due to factors like a dog's age, weight, overall health, and how well post-operative care guidelines are followed. Older or overweight dogs are at higher risk for delayed healing and implant failure because of increased strain on the joint. Inadequate rest, early activity, or infections can also cause setbacks.

Even with precise bone healing, some dogs may experience swelling, lameness, or implant-related issues. Being aware of these risks helps ensure timely intervention and optimal recovery. Proper monitoring, limited activity, and follow-up evaluations are crucial in reducing post-surgical complications.

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TL;DR: Possible Complications After TPLO Surgery

• Immediate complications: Infection, hemorrhage, implant loosening, excessive swelling, or premature suture removal.
• Mid-term complications: Delayed bone healing, seroma formation, nerve damage, tibial tuberosity fractures.
• Long-term complications: Patellar luxation, arthritis, meniscal injuries, persistent lameness, patellar ligament thickening.
• Severe complications: Osteomyelitis (bone infection), implant failure, chronic pain, or non-union of the bone.

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Immediate Post-Surgical Complications (First Few Days to Weeks After Surgery)

In the initial days after TPLO surgery, dogs are at risk for complications that can slow healing and cause discomfort. Careful monitoring and early intervention are crucial to ensuring a smooth recovery.

1. Infection at the Surgical Site

Infection is one of the most common early complications after TPLO surgery. It can happen if bacteria enter the surgical site, delaying healing and potentially affecting the implant.

Signs of infection include redness, swelling, warmth around the incision, pus-like discharge, an unpleasant odor, and increased pain or tenderness. Some dogs may also develop a fever or show signs of discomfort, such as excessive licking or reluctance to put weight on the affected leg.

Causes of infection include poor hygiene, contamination during or after surgery, excessive licking of the incision, and improper wound care. Dogs that lick or chew at their stitches introduce bacteria, increasing the risk of infection. Environmental factors, like a dirty bedding area, can also lead to bacterial growth.

Treatment options depend on how severe the infection is. Mild cases may be managed with oral antibiotics and regular wound cleaning using an antiseptic solution. More severe infections, especially those affecting deep tissues or the implant, require veterinary care.

This may include culture testing to identify the bacteria and, in rare cases, surgical removal of infected tissue. Preventive measures, such as using an Elizabethan collar (E-collar) and ensuring proper wound care, are essential to reducing the risk of infection.

2. Bone Infection (Osteomyelitis)

Osteomyelitis is a serious bone infection that affects deeper bone tissue and can compromise the TPLO implant. Unlike surface infections, osteomyelitis can cause long-lasting inflammation, bone damage, and implant failure.

Symptoms include ongoing swelling, increased pain, fever, pus draining from the incision, and slow healing. Affected dogs may become tired and unwilling to use the operated leg. In chronic cases, the infection can spread, causing a more widespread illness.

Risk factors include contamination during surgery, bacteria from an infected wound, or infections related to the implant. Dogs with weak immune systems or those in unclean environments after surgery are at higher risk.

Treatment involves strong antibiotic therapy, often based on bacterial culture results. In severe cases, surgery may be needed to remove infected bone tissue. If the implant is affected, it might need to be removed and replaced once the infection is under control. Early detection and strict hygiene are key to preventing osteomyelitis.

3. Implant Issues (Loosening, Breaking, or Failure)

Implant complications happen when the TPLO plate or screws don't work properly, causing instability in the knee joint. These issues can occur due to too much movement, poor implant placement, or infections that weaken the bone connection.

Signs of implant failure include ongoing limping, pain, swelling around the implant site, and unusual clicking or grinding sounds from the joint. In severe cases, the implant might shift, leading to bone misalignment. Dogs that suddenly become lame after surgery should be checked right away.

Causes include too much activity after surgery, improper bone healing, and mechanical stress on the implant. Infections can also weaken the bone and screws, increasing the chance of failure. Overweight dogs are at higher risk due to more pressure on the joint.

Possible corrective actions depend on how severe the issue is. Minor loosening might be managed with limited activity, while severe cases could need revision surgery to replace or reposition the implant. If there's an infection, the implant may need to be removed, followed by antibiotic treatment before placing a new implant.

4. Premature Suture Removal by the Dog

Dogs often lick or chew their sutures due to discomfort, irritation, or boredom. However, removing stitches too soon can reopen the surgical site, exposing tissues to infection and delaying healing.

Consequences of removing sutures include the wound reopening, a higher risk of infection, and excessive scarring. In severe cases, exposed tissues may dry out or become contaminated, requiring more surgery. If deeper sutures are disturbed, healing can be significantly delayed.

Preventive measures include using an Elizabethan collar (E-collar) to stop licking and chewing. Bandaging might help, but it must be done carefully to avoid moisture buildup, which can lead to bacterial growth. Supervision is crucial, especially in the first two weeks after surgery.

Providing distractions, like puzzle toys or chew treats, can help keep dogs from focusing on their incision. If stitches are removed too soon, a veterinarian should assess the wound immediately to decide if re-suturing or additional wound care is needed.

5. Hemorrhage During or After Surgery

Hemorrhage, or excessive bleeding, can happen during or after TPLO surgery due to blood vessel injury, clotting disorders, or improper post-operative care. While some mild bruising is normal, significant bleeding is a serious issue that needs immediate attention.

Symptoms of post-surgical hemorrhage include excessive blood oozing from the incision, swelling or bruising that gets worse over time, pale gums, rapid heart rate, and lethargy. In severe cases, internal bleeding may cause a swollen abdomen or breathing difficulties.

Causes include surgical trauma to blood vessels, clotting disorders like Von Willebrand’s disease, or post-operative strain on the incision site. Certain medications, such as NSAIDs and steroids, can also affect the ability to clot.

When to seek emergency vet care: If bleeding continues for more than a few hours, if the wound reopens, or if the dog shows signs of weakness and pale gums, immediate veterinary care is crucial. Treatment may involve pressure bandaging, fluid therapy, or surgical intervention to control internal bleeding. Quick action can prevent life-threatening complications and improve recovery outcomes.

Mid-Term Healing Complications (Weeks to Months Post-Surgery)

As the initial healing phase progresses, some dogs may experience complications that affect recovery in the weeks following surgery. Monitoring for persistent swelling, delayed healing, or mobility issues is essential to prevent long-term problems.

6. Swelling and Bruising at the Incision Site

Some swelling and bruising are expected after TPLO surgery as part of the body's normal healing process. Mild swelling around the incision site, along with light bruising, usually goes away within two weeks.

Concerning signs include swelling that doesn't go away or gets worse beyond the expected recovery time, extreme discoloration (deep purple or black bruising), excessive warmth, and increasing pain. These could indicate an infection, hematoma (blood accumulation), or poor circulation.

Managing swelling effectively requires early action. Cold therapy, like applying an ice pack wrapped in a towel for 10–15 minutes several times a day during the first 72 hours after surgery, helps reduce inflammation. After this initial period, warm compresses can be used to promote circulation. Anti-inflammatory medications, if prescribed by a veterinarian, can also help reduce swelling.

Strict rest and avoiding unnecessary movement help prevent further irritation. If swelling worsens or doesn't improve, a veterinarian should check the incision site to rule out complications such as infection or fluid buildup.

7. Seroma Formation (Fluid Accumulation)

A seroma is a fluid buildup under the skin near the surgical site. It can occur due to too much movement, surgical trauma, or minor irritation, which causes leakage from blood vessels and lymphatic tissues. Unlike an infection, a seroma is usually not painful and doesn't show redness or discharge.

It's important to tell the difference between normal swelling and a problematic seroma. A small, soft, and flexible swelling that doesn't cause discomfort is often a harmless seroma and may go away on its own. However, if seromas are large or don't go away, especially if they grow or become painful, a veterinarian should check them. Signs of infection, like warmth, redness, or pus, need immediate attention.

Treatment options depend on how severe the seroma is. Small seromas are usually managed by monitoring and using compression therapy. Reducing excessive movement can help decrease fluid buildup. Large seromas might need to be drained with a sterile needle.

If fluid continues to build up, a drain may be placed to stop further accumulation. Preventing too much movement and ensuring proper rest after surgery can help reduce the risk of seroma formation.

8. Nerve Damage Leading to Limb Numbness

Nerve damage after TPLO surgery is rare but can happen due to surgical manipulation near major nerve pathways. The peroneal nerve, which controls foot and lower limb function, is most at risk during tibial surgery. In some cases, swelling after surgery can also temporarily affect nerve function.

Symptoms of nerve damage include dragging the paw (knuckling), reduced sensation in the affected leg, lack of response to touch, or an unusual way of walking. Dogs may seem unable to place their foot properly on the ground. In severe cases, they may develop muscle wasting due to not using the limb for a long time.

Prognosis and recovery depend on how severe the nerve injury is. Mild nerve compression from swelling often gets better within weeks as the swelling goes down. Physical therapy, gentle massage, and controlled movement exercises can help with nerve recovery.

Severe nerve damage, such as a completely severed nerve, has a poorer outlook and may require assistive devices or surgery. Close monitoring and early rehabilitation improve the chances of functional recovery.

9. Delayed Bone Healing or Non-Union

Bone healing after TPLO surgery usually takes 8–12 weeks, but sometimes healing is delayed or does not happen properly (non-union). Several factors can affect bone healing, including poor nutrition, too much activity, infection, or improper implant placement.

Signs of delayed healing include prolonged limping, ongoing swelling around the surgical site, and discomfort that lasts beyond the expected recovery time. X-rays may show incomplete bone fusion at the osteotomy site, indicating slowed healing. If not addressed, delayed healing can lead to implant failure or instability in the knee joint.

Treatment approaches focus on encouraging bone regrowth. A veterinarian may suggest calcium and vitamin D supplements to support bone health. Strict activity restriction is essential to prevent too much movement at the healing site. If an infection is suspected, antibiotics are prescribed.

In severe cases, additional surgery may be needed to replace hardware, perform a bone graft, or stimulate healing with advanced techniques like bone-stimulating proteins. Early intervention increases the chances of full recovery and proper joint stabilization.

10. Tibial Tuberosity Fractures

A tibial tuberosity fracture is a rare but serious issue that can happen after TPLO surgery. The tibial tuberosity is the bony bump where the patellar tendon attaches, and too much strain can cause it to fracture, especially in large, active dogs or those not properly cared for after surgery.

Symptoms of a tibial tuberosity fracture include sudden pain, reluctance to put weight on the leg, localized swelling, and knee joint instability. Some dogs may walk abnormally or have trouble extending their leg. This fracture is usually diagnosed with X-rays, which show a break near the TPLO osteotomy site.

Treatment depends on the fracture's severity. Minor fractures may heal with strict rest, pain management, and controlled rehabilitation. More severe cases require surgery, which may involve adding screws or wire to stabilize the fracture.

Proper post-operative care, including limited movement and weight management, is crucial to prevent tibial tuberosity fractures. Early detection and appropriate treatment improve recovery and help restore normal joint function.

Long-Term Complications (Months to Years Post-Surgery)

While most dogs recover well after TPLO surgery, some may develop complications months or even years later. These long-term issues can impact mobility and joint health, requiring ongoing management and veterinary care.

11. Patellar Luxation (Kneecap Dislocation)

TPLO surgery changes how the knee works, which can sometimes affect the position of the patella (kneecap). While TPLO stabilizes the knee joint by adjusting the tibial plateau, it may lead to patellar instability, especially in small-breed dogs or those with existing knee issues.

Symptoms of patellar luxation include a skipping gait, where the dog briefly lifts the leg before walking normally again. There may also be sudden pain, occasional limping, or trouble putting weight on the leg. Some dogs might be hesitant to jump or do high-impact activities.

Treatment options depend on how severe the condition is. Mild cases can be managed with physical therapy, exercises to strengthen muscles, and weight management to lessen stress on the knee.

In severe cases, where the patella often dislocates and causes discomfort, surgery may be needed to realign the patellar groove or tighten the soft tissues around the knee. Long-term monitoring and controlled exercise can help reduce the risk of further joint instability.

12. Patellar Ligament Thickening or Desmopathy

After TPLO surgery, the patellar ligament (which connects the kneecap to the tibia) may thicken due to increased stress and changes in the tissue as it heals. This condition, known as desmopathy, is a response to the altered mechanics of the knee and may cause discomfort or limit mobility.

How it impacts mobility: Thickened patellar ligaments can lead to stiffness, a reduced range of motion, and occasional lameness. Dogs might have trouble fully extending the knee or feel discomfort when walking on uneven surfaces. In some cases, ligament thickening can contribute to patellar luxation or chronic pain.

Treatment and management focus on reducing inflammation and keeping the joint flexible. Cold laser therapy, controlled exercise, and joint supplements (like glucosamine and chondroitin) may help maintain ligament health.

In severe cases where thickening causes functional problems, physical therapy, anti-inflammatory medications, or, in rare instances, surgery may be necessary. Gradually returning to activity and avoiding high-impact exercises can help minimize stress on the ligament.

13. Meniscal Injury or Tear

The meniscus is a cartilage structure that cushions the knee joint. While TPLO surgery stabilizes the knee, it does not remove the risk of meniscal injuries. Sometimes, leftover instability or stress from implants can cause the meniscus to wear down or tear.

Symptoms of meniscal damage include a clicking or popping sound when the dog moves, occasional or constant lameness, reluctance to use the affected leg, and discomfort when bending the knee. Some dogs may suddenly experience more pain after initially showing signs of recovery.

Treatment options depend on how severe the tear is. Mild cases might be managed with pain relief, joint supplements, and controlled exercise. However, if a meniscal tear causes ongoing pain and instability, surgery is often needed.

This may involve a partial meniscectomy, where the damaged part is removed, or meniscal repair if the cartilage can be saved. Long-term management includes weight control, low-impact exercise, and joint-protective therapies to reduce stress on the knee.

14. Persistent or Recurrent Lameness

While temporary lameness is expected during TPLO recovery, persistent or recurrent lameness months or years after surgery indicates an underlying issue. Some dogs may initially regain function but later experience setbacks.

When lameness is normal vs. a complication: Mild stiffness after long periods of rest or in cold weather is common in post-TPLO dogs, especially as they age. However, continuous limping, favoring one leg, or worsening mobility suggests a complication such as implant issues, nerve damage, or progressive joint disease.

Common causes include implant loosening, nerve irritation, arthritis, or secondary joint problems like patellar luxation or meniscal injury. Improper post-op rehabilitation can also lead to muscle weakness, causing uneven weight distribution.

Rehabilitation options focus on hydrotherapy, physiotherapy, and pain relief through NSAIDs or joint supplements. Weight control is crucial in reducing stress on the knee. For severe cases, advanced pain management options like platelet-rich plasma (PRP) therapy, acupuncture, or even surgical revision may be necessary.

15. Development of Arthritis After Surgery

Even after successful TPLO surgery, some dogs develop arthritis over time due to joint wear and tear. While TPLO improves knee stability, it doesn't prevent degenerative joint disease (DJD), especially in older or previously injured dogs.

Why arthritis develops: Chronic inflammation, ongoing joint stress, or minor imperfections in bone healing can lead to cartilage breakdown. Dogs with previous CCL damage, obesity, or an uneven gait are at higher risk.

Symptoms include joint stiffness, difficulty getting up, reluctance to move, limping, and swelling around the knee. Dogs may struggle with stairs, hesitate before jumping, or feel discomfort after exercise. Symptoms often worsen in cold weather or after long periods of inactivity.

Long-term management focuses on weight control, joint supplements (glucosamine, chondroitin, omega-3s), anti-inflammatory treatments (NSAIDs, corticosteroid injections), and physical therapy. Low-impact activities like swimming or controlled walks can maintain muscle strength while reducing joint stress.

In advanced cases, regenerative therapies such as stem cell treatment or PRP injections may provide relief. Managing arthritis proactively helps maintain mobility and quality of life for years after surgery.

How to Reduce the Risk of TPLO Complications

Minimizing complications after TPLO surgery requires strict post-operative care, proper wound management, and ongoing rehabilitation.

Following veterinary instructions and ensuring a controlled recovery environment significantly improve surgical outcomes.

Strict post-op care

Strict post-op care is essential in preventing implant failure, infections, and delayed healing. Dogs must have limited movement for the first few weeks, avoiding running, jumping, or sudden movements that can strain the surgical site. A crate or confined space ensures controlled rest, while leash-walks allow gradual reintroduction to activity.

Proper wound care and hygiene

Proper wound care and hygiene reduce infection risks. The surgical incision should be checked daily for redness, swelling, or discharge. Using veterinary-recommended antiseptics and preventing licking (via an Elizabethan collar) are key to avoiding contamination.

Many surgeons now use Simini Protect Lavage, a non-antibiotic surgical lavage, to reduce bacterial contamination and biofilm formation, lowering the risk of post-surgical infections.

Rehabilitation and physical therapy

A well-structured rehabilitation plan is essential for restoring mobility, muscle strength, and joint flexibility after TPLO surgery. Early intervention helps prevent stiffness, muscle atrophy, and long-term mobility issues.

Hydrotherapy (underwater treadmill or swimming) provides low-impact exercise, reducing strain on healing joints while strengthening muscles. Passive range-of-motion exercises improve flexibility, while controlled weight-bearing activities help rebuild strength without overloading the surgical site.

Rehabilitation also includes balance exercises, cold laser therapy, and massage therapy, which aid circulation and reduce post-surgical discomfort. A veterinarian or canine rehabilitation specialist can create a customized recovery plan to ensure optimal healing and long-term joint health.

Lastly, early detection improves recovery. Watching for limping, excessive swelling, or behavioral changes helps identify issues before they get worse.

When to Call Your Vet

Recognizing when to seek veterinary care is crucial for preventing serious TPLO complications. Emergency signs that need immediate attention include excessive bleeding, severe swelling, ongoing pain, fever, an open incision, or a sudden inability to bear weight on the operated leg.

Mild symptoms like slight swelling, occasional limping, or minor wound discharge should still be checked if they persist or get worse. Delayed healing or changes in behavior may indicate an underlying issue.

Regular post-op checkups are important for monitoring bone healing, implant stability, and joint function. Early intervention helps prevent complications, ensuring a smooth and successful recovery for your dog.

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Read more about -

• TPLO failure symptoms
• Common causes of limping in dogs post-TPLO surgery
• Before and after TPLO surgery: Dog health & recovery timeline
• TPLO surgery for older dogs: Is it a worthwhile option?

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Conclusion

TPLO surgery is very effective for stabilizing a dog’s knee, but complications can occur without proper post-operative care. Understanding potential risks and taking preventive steps can ensure a smoother recovery.

1. Strict post-op care – Limiting movement, using an E-collar, and following vet instructions help prevent implant failure and infections.
2. Proper wound hygiene – Keeping the incision clean and watching for redness, swelling, or discharge reduces infection risks.
3. Early detection of complications – Signs like persistent limping, fever, or swelling should lead to immediate veterinary evaluation.
4. Rehabilitation and physical therapy – Hydrotherapy and controlled exercises help with muscle recovery and joint flexibility.
5. Regular vet checkups – Routine follow-ups ensure proper bone healing, implant stability, and early complication management.
6. Using advanced surgical solutions – Many surgeons use Simini Protect Lavage to reduce infection risks and improve post-surgical outcomes.
7. Long-term joint health management – Weight control, joint supplements, and arthritis prevention strategies enhance mobility and quality of life.

By staying proactive and working closely with your veterinarian, you can minimize complications and support your dog’s full recovery after TPLO surgery.

FAQs

What are the long-term complications of TPLO surgery?

Long-term complications can include patellar luxation, arthritis, implant failure, meniscal injuries, and persistent lameness. Some dogs may develop patellar ligament thickening or nerve-related mobility issues. While many dogs recover well, maintaining joint health, weight control, and regular vet checkups helps minimize long-term risks.

What to watch for after TPLO surgery?

Monitor for swelling, redness, discharge, excessive pain, fever, or sudden lameness. Signs of complications include persistent limping, wound infection, delayed healing, or implant issues. If the dog refuses to bear weight or shows increased discomfort over time, a veterinary evaluation is necessary to rule out serious post-surgical issues.

What are the mistakes for TPLO?

Common mistakes include allowing too much activity too soon, neglecting wound care, not using an E-collar, missing follow-up visits, and improper rehabilitation. Failing to restrict movement can lead to implant failure, delayed bone healing, or reinjury. Strict adherence to post-op care reduces these risks.

What is the complication rate of TPLO?

The overall complication rate for TPLO surgery ranges from 10-34%, with most being minor issues like swelling or mild infections. Serious complications, such as implant failure, fractures, or osteomyelitis (bone infection), occur in a smaller percentage of cases. Proper post-operative care significantly reduces complication risks.

Do dogs fully recover from TPLO surgery?

Most dogs fully recover within 12-16 weeks and regain normal mobility. With proper rehabilitation, they can return to an active lifestyle, including running and playing. However, some may develop mild stiffness or arthritis later in life. Regular exercise, weight control, and joint supplements help maintain long-term joint health.

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Step #1

Getting Ready

Ensuring a clean surgical field starts with proper skin preparation. This video demonstrates the best practices for:

Shaving the patient – Achieving a close, even shave while minimizing skin irritation

The Dirty Scrub – The initial skin prep step to remove surface debris and reduce bacterial load before the sterile scrub.

Following these techniques helps reduce infection risk and improve surgical outcomes. Watch the video to see how it’s done effectively!

Step  #2

Reduce Your Risks

Many surgeons are shocked to find out that their patients are not protected from biofilms and resistant bacteria when they use saline and post-op antibiotics.  

That’s Where Simini Comes In.

Why leave these risks and unmanaged?  Just apply Simini Protect Lavage for one minute. Biofilms and resistant bacteria can be removed, and you can reduce two significant sources of infection.

Protect Your Patients

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Preventing surgical infections is critical for patient safety and successful outcomes. This course covers:

Aseptic techniques – Best practices to maintain a sterile field.

​Skin prep & draping – Proper methods to minimize contamination.

​Antibiotic stewardship – When and how to use perioperative antibiotics effectively.

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Why Confinement Matters After TPLO Surgery

Confinement is one of the most important parts of TPLO recovery. After surgery, your dog’s knee is healing and not yet stable. Limiting movement protects the surgical site and gives the bone, soft tissues, and implant time to settle and heal properly.

Without proper confinement, your dog may jump, run, or twist the leg—movements that can cause serious problems. These actions can lead to re-injury, implant failure, or delayed healing. Even a short burst of energy during the early weeks can undo the surgical repair.

Use a crate, pen, or small room with non-slip flooring to keep your dog calm and safe. Always use a leash when outside, even for bathroom breaks. Proper confinement supports faster healing, reduces pain, and lowers the risk of complications, helping your dog return to normal life sooner.

Choosing the Right Confinement Setup

Crate or Small Room

A crate is one of the safest ways to confine your dog after TPLO surgery. It limits movement while allowing rest in a cozy, secure space. Crates help prevent jumping, running, or sudden twisting that can damage the healing leg.

Choose a crate that’s large enough for your dog to stand, turn around, and lie down comfortably, but not so big that they can run inside it. Use soft bedding and avoid wire flooring. A small, quiet room can also work if the crate feels too restrictive for your dog.

Exercise Pen (X-pen) as an Alternative

An exercise pen (X-pen) is a good option for dogs who don’t do well in crates. It allows more room to stretch while still limiting unsafe movement. Use it only if your dog is calm and not likely to jump or push against the sides.

To make it secure, place it on non-slip flooring and anchor the panels so they don’t move. Avoid putting toys that may cause too much excitement inside. An X-pen works best when placed in a quiet corner of the home, away from distractions.

Baby Gates and Physical Barriers

Baby gates or other barriers can help block off areas like stairs, hallways, or rooms where your dog may try to run or jump. They’re useful when using a small room as a recovery space or to limit access within your home.

Make sure gates are tall enough and securely installed to prevent your dog from pushing them over. Combine gates with closed doors or blocked furniture to create a safe recovery zone that’s quiet, has soft bedding, and keeps your dog close to you while staying confined.

Making the Space Safe and Comfortable

Use Non-Slip Floors

Slick floors like tile or hardwood can be dangerous after TPLO surgery. Dogs recovering from surgery may slip easily, which can strain the healing leg or even damage the implant. To prevent falls, cover the floor with non-slip rugs, yoga mats, or rubber-backed runners.

These give your dog better grip when walking or shifting positions. Make sure mats lie flat to avoid tripping. A stable, slip-free surface gives your dog more confidence to move safely and supports better recovery during the early healing stages.

Remove Hazards and Obstacles

To keep your dog’s recovery area safe, remove anything that could cause injury or discomfort. Take away slippery throw rugs, which can slide underfoot. Watch out for sharp corners, unstable furniture, or clutter your dog could bump into or trip over.

Keep electrical cords out of reach and make sure the area is free from chewable or breakable items. A hazard-free zone gives your dog a calm, injury-free space to rest and heal without the risk of accidents or stress.

Prevent Access to Furniture and Stairs

Jumping on or off furniture and climbing stairs is risky after TPLO surgery. These movements can place too much pressure on the healing leg and lead to setbacks. Use baby gates or closed doors to block off stairs and rooms with couches or beds.

If your dog must use stairs to access the outdoors, consider using a ramp or carry them with proper support. Keeping your dog grounded and away from heights protects the surgical site and helps prevent reinjury.

Add Soft Bedding and Essentials

Comfort is key during recovery. Use soft, supportive bedding to cushion your dog’s joints and help them relax. Orthopedic dog beds or thick blankets work well. Place food and water bowls within easy reach, so your dog doesn’t need to walk far.

Keep the area clean by washing bedding often and wiping up spills. Good hygiene prevents infections and keeps the recovery space fresh. A comfortable, well-stocked setup reduces stress, supports healing, and helps your dog feel calm and cared for.

Managing Daily Routines in Confinement

Always Use a Leash Outside the Confinement Area

After TPLO surgery, always keep your dog on a short leash, even indoors, when outside the recovery space. This includes bathroom breaks or short walks across the house. Dogs can get excited quickly and make sudden movements that may harm the healing leg.

Using a leash helps you control their speed and direction. It also prevents jumping, running, or slipping on smooth floors. Calm, guided movement keeps your dog safe and reduces the risk of re-injury during recovery.

Stick to a Strict Potty Schedule

Maintaining a consistent potty routine helps reduce stress for both you and your dog. Take your dog out at the same times each day using a leash. Always go to the same spot, so they recognize it as their bathroom area. Avoid long walks or distractions.

A set schedule helps regulate their body, keeps outings short, and makes it easier to control their movement. Staying consistent also reduces the chances of indoor accidents and supports a calm recovery environment.

Supervise Whenever Out of Confinement

Your dog should never be out of the recovery area without supervision, even for short periods. No off-leash time is allowed during the early weeks. Watch closely for signs of restlessness, like pacing, whining, or sudden bursts of energy.

These can lead to unsafe movement that may damage the healing leg. Always stay nearby and use a leash to guide them. Close supervision ensures your dog stays calm and safe, giving the surgery site time to heal properly.

Final Tips for a Smooth Recovery

A calm mind is just as important as a healing body. Keep your dog mentally calm by creating a peaceful environment with limited noise and stimulation. If needed, you can introduce safe mental enrichment later in recovery, like puzzle toys or slow feeders, but only with your vet’s approval.

If you have concerns about confinement, such as anxiety or restlessness, talk to your vet. They can suggest calming aids, safe adjustments, or behavior tips to help your dog settle.

As your dog heals, you may need to adjust the recovery space. For example, you can allow more room to stretch or reposition food and water bowls as mobility improves. Always make changes based on your vet’s guidance. Recovery takes time, but with patience, proper care, and the right setup, your dog will be on the path to a healthy, active life again.

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Read more about:

• TPLO failure symptoms
• Long-term outcomes of TPLO surgery
• Common causes of limping in dogs post-TPLO surgery
• Preparing for your dog’s TPLO surgery

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FAQs

How to keep a dog calm after TPLO surgery?

Keep your dog in a quiet, confined space like a crate or small room. Avoid visitors, loud noises, and playtime. Use soft bedding and stick to a calm routine. If needed, ask your vet about safe calming aids or anxiety support during the early recovery period.

Can I leave my dog alone after TPLO surgery?

Yes, but only if your dog is safely confined in a crate or pen where they can’t jump or move around too much. Make sure they have food, water, and can’t reach the incision. Avoid leaving them alone for long periods, especially during the first week.

Can my dog walk around the house after TPLO?

No, free movement around the house is not safe during early recovery. Your dog should only walk on a leash for short bathroom breaks. Letting them walk freely can risk injury, implant damage, or slower healing. Always supervise and limit movement as advised by your vet.

How long is a dog in pain after TPLO?

Most dogs experience some pain or discomfort for the first 7–10 days after surgery. Pain is usually well managed with vet-prescribed medications. If your dog seems uncomfortable beyond that or shows signs of distress, contact your vet for a recheck or medication adjustment.

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What Is Bilateral TPLO Surgery?

Tibial Plateau Leveling Osteotomy (TPLO) is a surgical procedure used to treat cranial cruciate ligament (CCL) rupture in dogs. Instead of replacing the torn ligament, TPLO alters the tibial plateau angle, stabilizing the knee joint and reducing abnormal movement.

Bilateral TPLO surgery is performed when both knees require correction. Some dogs suffer CCL injuries in both hind limbs, either simultaneously or within a short period. In such cases, a surgeon may recommend performing TPLO on both knees in a single procedure or as staged surgeries.

Large, active breeds like Labrador Retrievers, Rottweilers, Golden Retrievers, and German Shepherds are more prone to CCL injuries due to their size and activity level. Obesity, genetics, and structural predisposition also contribute to ligament degeneration, making bilateral TPLO necessary for some dogs. Early intervention helps restore mobility and prevent long-term joint damage.

When Is Double or Bilateral TPLO Surgery Necessary?

Some dogs develop cranial cruciate ligament (CCL) injuries in both knees, either at the same time or within a few months. This often occurs due to genetic factors, excessive strain on the healthy limb after an initial injury, or progressive ligament wear in both knees. When both knees are unstable, bilateral TPLO surgery is necessary to restore mobility and prevent further joint damage.

Dogs needing bilateral TPLO often show signs like severe limping, difficulty standing up, reluctance to walk or play, and an unusual sitting posture. They may shift their weight excessively, struggling to support themselves on either leg.

Veterinarians determine the need for bilateral TPLO through a detailed orthopedic exam, gait analysis, and imaging tests like X-rays. If both knees are significantly unstable, vets may recommend simultaneous TPLO to correct both knees in one procedure.

However, for older dogs or those with other health issues, a staged approach—operating on one leg first and the other after recovery—may be safer to reduce surgical risks.

Simultaneous vs. Staged TPLO Surgery: What’s the Best Choice?

When a dog needs TPLO on both knees, veterinarians consider two approaches: simultaneous TPLO (operating on both legs at once) or staged TPLO (operating on one leg first and the other after recovery).

Simultaneous TPLO

Simultaneous TPLO offers the advantage of a single anesthesia event and a shorter overall recovery period. Dogs regain balanced mobility faster since both knees heal together.

However, post-surgical care is more challenging because the dog cannot rely on a strong leg for support, requiring owners to provide intensive assistance. Risks include increased surgical stress and a higher chance of post-operative complications like swelling or infection.

Staged TPLO

Staged TPLO involves operating on one knee first, allowing recovery before addressing the second leg. This approach reduces surgical risk, making it ideal for older dogs, those with other health issues, or those struggling with post-surgical pain. However, the overall treatment period is longer, and the dog may continue to experience discomfort in the untreated leg during the recovery phase.

Veterinarians decide the best approach based on factors like the dog’s overall health, weight, pain tolerance, and the owner’s ability to manage post-surgical care.

Large dogs with strong front limbs may handle simultaneous TPLO better, while smaller or weaker dogs may benefit from a staged approach.

Benefits of Doing Bilateral TPLO Surgery at Once

For dogs needing TPLO on both knees, opting for simultaneous bilateral TPLO surgery has several advantages compared to staging the procedures months apart.

• One major benefit is a faster overall recovery period. When both knees are corrected in a single surgery, the dog undergoes just one healing phase rather than two separate ones. This means they can return to normal activity sooner compared to waiting for two rounds of surgery and rehabilitation.
• Another advantage is lower long-term costs. While simultaneous TPLO may have a higher upfront expense, it often reduces overall costs by avoiding duplicate anesthesia, hospitalization, and post-operative care fees associated with two separate surgeries. Pet owners also save on pain medications and follow-up appointments.
• Bilateral TPLO also helps prevent excessive strain on the unoperated leg. When only one knee is repaired first, the dog must rely heavily on the untreated leg, which can worsen ligament damage or lead to muscle imbalances. Simultaneous TPLO eliminates this risk by addressing both knees at once, ensuring balanced weight distribution during recovery.
• Lastly, dogs who undergo bilateral TPLO often experience better mobility post-recovery. When both knees heal together, they regain strength and stability more evenly, allowing for a smoother transition back to normal activities. This approach minimizes long-term joint issues and improves overall quality of life.

For young, healthy, and active dogs, bilateral TPLO surgery can be the best option for a quicker and more effective recovery.

Read more about - Long-Term Outcomes of TPLO Surgery

How Double TPLO Surgery Is Performed

Step 1: Pre-Surgery Preparation

Before bilateral TPLO surgery, veterinarians perform a thorough evaluation, including X-rays to assess the tibial plateau angle and confirm the need for surgery.

Bloodwork ensures the dog is healthy enough for anesthesia. The dog is then sedated, intubated, and placed under general anesthesia. The surgical area on both knees is shaved and disinfected to minimize infection risk.

Step 2: Surgical Process

During the procedure, the surgeon makes an incision over each knee to access the tibia. A specialized oscillating saw is used to cut and rotate the tibial plateau, adjusting its angle to stabilize the joint and eliminate abnormal motion caused by cranial cruciate ligament (CCL) rupture. Once repositioned, a metal plate and screws are secured to hold the bone in place, ensuring proper healing and function.

To reduce the risk of biofilm formation and post-surgical infections, many surgeons use advanced solutions like Simini Protect Lavage. This non-antibiotic lavage solution helps flush out bacteria and prevent biofilm development, significantly lowering the chances of infection and promoting a safer recovery.

Combined with sterile surgical techniques and post-operative antibiotics, these measures enhance healing outcomes and minimize complications.

Step 3: Post-Surgical Stabilization and Suturing

Once both knees are stabilized, the surgeon checks for proper alignment. Soft tissues and muscles are carefully repositioned before closing the incision with sutures or staples. A sterile bandage may be applied to protect the area.

Step 4: Immediate Post-Op Monitoring at the Vet Clinic

After surgery, the dog is moved to recovery and closely monitored for pain, bleeding, or complications. Pain medications and antibiotics are administered, and vets ensure the dog is stable before planning the transition home. Owners receive detailed post-op care instructions for managing pain, mobility, and incision care.

Risks and Potential Complications of Double TPLO Surgery

While bilateral TPLO surgery is highly effective, it comes with risks and potential complications that pet owners should be aware of.

• One significant concern is the risk of infection, which can occur at the surgical site or internally around the implants. Infection risk is minimized by using sterile surgical techniques, prescribing antibiotics, and ensuring proper at-home wound care. Keeping the incision site clean and preventing the dog from licking or biting the sutures is essential for avoiding post-operative infections.
• Another risk is delayed healing, as both legs are recovering at the same time. Unlike a staged TPLO, where the healthy leg supports weight during recovery, dogs undergoing bilateral TPLO may struggle with mobility. Strict activity restrictions, proper pain management, and joint-supporting supplements can help promote faster healing.
• Implant failure or loosening is another complication that may arise, especially in highly active dogs or those with improper post-op care. Excessive movement or jumping can put stress on the surgical plates and screws, potentially leading to implant shifting or breakage. This can require additional surgery to correct.
• Lastly, anesthesia-related risks and post-operative pain are concerns with any major surgery. Though modern anesthetics are generally safe, dogs with underlying health conditions may face complications. Post-op pain is managed with medications, but owners must monitor for signs of discomfort, swelling, or limping.

Following the vet’s post-op care instructions, including strict rest and controlled rehabilitation, significantly reduces these risks and ensures a smoother recovery.

What to Expect After Double TPLO Surgery

First 24–48 Hours: Managing Pain, Limited Movement

Immediately after surgery, your dog will experience grogginess from anesthesia and discomfort from the procedure. Pain management is crucial, with vets prescribing anti-inflammatory medications and opioids for relief.

Movement should be extremely limited, and your dog may need assistance standing or going outside for bathroom breaks. Using a harness or sling can help support their weight. Swelling around the incisions is normal, but excessive redness, oozing, or heat could indicate infection.

First 2 Weeks: Strict Rest, Keeping the Dog Confined

During this period, strict crate rest or confinement in a small, quiet space is essential. Jumping, running, or sudden movements should be avoided to prevent stress on the healing bones.

Short, controlled leash walks for bathroom breaks are allowed, but no excessive movement. The surgical site should be monitored daily for any signs of infection or swelling.

Weeks 3–6: Gradual Improvement, Light Movement

By the third week, mild weight-bearing on both legs should improve, but full activity is still restricted. Short, controlled leash walks (5-10 minutes) may be introduced if the vet approves. Most dogs begin regaining stability, but muscle weakness is common.

Weeks 6–12: Rehab Starts, Monitoring for Complications

With vet approval, rehabilitation exercises such as slow leash walks, underwater treadmill therapy, or passive range-of-motion exercises can begin. Any signs of excessive limping, pain, or swelling should be reported to the vet immediately.

Full Recovery Timeline: When the Dog Can Walk, Run, and Return to Normal

By 12–16 weeks, most dogs can walk comfortably, and by 4–6 months, they regain full mobility, including running and playing. However, high-impact activities should be reintroduced cautiously under veterinary guidance to prevent re-injury.

Read more about - Post-Surgery Recovery After TPLO in Dogs

Pain Management and Medications After Surgery

Managing pain effectively after bilateral TPLO surgery is crucial for a smooth recovery. Veterinarians typically prescribe a combination of NSAIDs (non-steroidal anti-inflammatory drugs), opioids, and supplements to control pain and inflammation.

• NSAIDs (e.g., Carprofen, Meloxicam) help reduce inflammation and swelling. These should always be given with food to prevent stomach irritation.
• Opioids (e.g., Tramadol, Buprenorphine) provide stronger pain relief in the first few days post-surgery, especially when discomfort is severe.
• Joint supplements (e.g., glucosamine, chondroitin, omega-3 fatty acids) support long-term joint health and aid in recovery.

To manage swelling and discomfort, cold therapy (icing the surgical area for 10–15 minutes, 2–3 times a day) can help reduce inflammation. Anti-inflammatory treatments, including prescribed medications and natural supplements, may further support healing.

It’s important to monitor for signs of excessive pain, such as persistent whining, heavy panting, restlessness, refusal to move, or loss of appetite. If your dog shows these symptoms despite medication, or if swelling and redness worsen, contact your vet immediately. Proper pain management not only ensures comfort but also promotes faster recovery and prevents complications.

Importance of Physical Therapy and Rehabilitation

Physical therapy plays a critical role in speeding up healing and restoring mobility after bilateral TPLO surgery. Without proper rehabilitation, dogs may experience muscle atrophy, stiffness, or prolonged discomfort.

Controlled movement helps strengthen the muscles around the knee joints, improves flexibility, and ensures a smoother recovery.

Recommended Rehab Exercises:

• Passive stretching – Gentle range-of-motion exercises help prevent stiffness and improve flexibility. These should be done 2–3 times daily with slow, controlled movements.
• Water therapy (underwater treadmill or swimming) – This is an excellent low-impact exercise that builds strength while reducing stress on the joints. Typically introduced 4–6 weeks post-surgery, if approved by the vet.
• Controlled leash walks – Short, slow walks (starting at 5 minutes per session) encourage weight-bearing and muscle engagement. Walk duration is gradually increased over time.

When to Start Rehab and Frequency:

Most rehab exercises begin around 2–3 weeks post-surgery, depending on the dog’s progress. Sessions should be daily but short to avoid fatigue. A structured rehabilitation plan, guided by a veterinarian or certified canine rehab therapist, ensures the safest and most effective recovery. Proper rehab improves strength, reduces re-injury risks, and helps dogs regain full mobility faster.

Home Care and Activity Restrictions for Recovery

Creating a safe and controlled recovery space is essential after bilateral TPLO surgery. A quiet, confined area with non-slip flooring, soft bedding, and limited space to move helps prevent accidental injuries. Using a crate or a small enclosed area with baby gates ensures your dog stays in a controlled environment while healing.

Restricting movement is crucial in the first 8–12 weeks. Jumping, running, or climbing stairs must be avoided, as sudden movements can put stress on healing bones and implants. Furniture should be blocked off, and leash walks should be strictly supervised.

For mobility assistance, supportive slings or harnesses (such as a rear-lift harness) help dogs stand up, walk for bathroom breaks, and shift weight safely. This is particularly important in the first few weeks when both legs are weak.

Since physical activity is limited, mental stimulation is key to preventing boredom and restlessness. Provide interactive toys, puzzle feeders, and scent-based games to keep your dog engaged without physical strain.

Spending extra time with your dog through gentle petting and calm interaction helps keep them relaxed and comfortable throughout recovery. Careful management ensures a smoother healing process and reduces complications.

Cost of Double or Bilateral TPLO Surgery and Financial Considerations

The cost of bilateral TPLO surgery varies depending on location, veterinary expertise, and hospital fees. In the U.S., the average cost for a single TPLO ranges from $3,500 to $6,000 per knee, meaning bilateral TPLO can cost $7,000 to $12,000. In other regions, such as Canada, the U.K., or Australia, prices may be slightly lower or higher based on veterinary costs and currency differences.

Factors affecting cost include:

• Geographic location – Urban areas with higher living costs tend to have more expensive veterinary services.
• Veterinarian experience – Board-certified surgeons may charge higher fees due to their expertise.
• Hospital fees – Costs for anesthesia, post-op care, medications, and follow-up visits add to the total.

Does pet insurance cover TPLO surgery? Coverage depends on the policy. Many comprehensive pet insurance plans cover TPLO if it’s not a pre-existing condition. Some require a waiting period before covering ligament injuries.

Financing options include payment plans through veterinary clinics, CareCredit, Scratchpay, or pet-specific credit programs to help spread out the cost. Some non-profits and crowdfunding platforms also assist pet owners facing high medical expenses.

Read more about - How Much Does TPLO Surgery Cost?

Final Thoughts on Double or Bilateral TPLO Surgery

Bilateral TPLO surgery is a highly effective solution for dogs with cranial cruciate ligament injuries in both knees. While the procedure requires a significant commitment in terms of cost, recovery time, and post-op care, the long-term benefits—restored mobility, reduced pain, and improved quality of life—make it worth considering for most dogs.

If your dog is struggling with severe knee instability but surgery isn’t an immediate option, consult your vet about alternative treatments like physical therapy, joint supplements, weight management, or custom braces. However, these may only provide temporary relief rather than a permanent solution.

For pet owners navigating this process, patience and commitment are key. Recovery may feel overwhelming, but with proper care and rehabilitation, most dogs return to an active, happy life. Stay in close contact with your vet, follow post-op guidelines, and trust the healing process.

‍

Read more about -

• TPLO failure symptoms
• Common causes of limping in dogs post-TPLO surgery
• Before and after TPLO surgery: Dog health & recovery timeline
• TPLO surgery for older dogs: Is it a worthwhile option?

FAQs

Can a dog have TPLO surgery on both legs?

Yes, a dog can undergo bilateral TPLO surgery if both cranial cruciate ligaments (CCLs) are torn or unstable. This can be done simultaneously or in a staged approach. Simultaneous TPLO addresses both knees in one procedure, while staged TPLO repairs one knee first, followed by the second after recovery. The choice depends on the dog’s health and the surgeon’s recommendation.

How much does bilateral TPLO surgery cost?

The cost of bilateral TPLO surgery varies by location and veterinary clinic. In the U.S., it typically ranges from $7,000 to $12,000 for both knees. Factors such as surgeon expertise, hospital fees, medications, and follow-up care affect the final price. Some pet insurance policies may cover TPLO if it is not a pre-existing condition, and financing options are available at many clinics.

What is the recovery time for bilateral TPLO surgery in dogs?

Full recovery from bilateral TPLO surgery typically takes 12 to 16 weeks. In the first 2 weeks, strict rest and pain management are essential. By weeks 3 to 6, controlled movement starts. Around weeks 6 to 12, rehab exercises begin, gradually improving strength. Most dogs return to normal activity by 4 to 6 months, but high-impact activities should be reintroduced cautiously.

What is bilateral TPLO?

Bilateral TPLO refers to Tibial Plateau Leveling Osteotomy surgery performed on both knees to treat cranial cruciate ligament (CCL) tears. It stabilizes the knee joint by altering the tibial plateau angle, preventing excessive movement. This procedure is common in large, active dogs or those genetically prone to CCL injuries. It can be done simultaneously or in two separate surgeries.

What happens if a dog tears both CCLs?

If a dog tears both cranial cruciate ligaments (CCLs), it may experience severe pain, difficulty standing, and an unstable gait. Without surgery, arthritis and joint degeneration can develop quickly. Treatment options include bilateral TPLO surgery, custom knee braces, weight management, and physical therapy. Surgery is typically the best option for restoring long-term mobility and preventing further joint damage.

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TPLO (Tibial Plateau Leveling Osteotomy) surgery is known as one of the best treatments for cranial cruciate ligament (CCL) tears in dogs, similar to ACL injuries in humans. This surgery has greatly improved outcomes for dogs, allowing them to move freely and live without pain.

Despite its success, there are several myths about TPLO surgery. These misconceptions can cause hesitation in recommending or choosing this procedure, which might delay the best care for dogs in need.

Knowing the facts about TPLO surgery is important for making informed decisions about your dog's health. In this article, we will clear up common myths, providing clear and evidence-based information to help pet owners confidently choose the best care for their furry friends.

Myth 1 - TPLO Surgery Isn't Always Necessary for ACL Tears

While TPLO surgery is the best treatment for CCL tears, it isn't necessary for every case. For mild or partial tears in less active dogs, alternatives like the lateral suture technique or conservative management, including physical therapy and weight management, can be effective. These options are often best for smaller breeds or older dogs with minimal joint instability.

In our experience, TPLO surgery is the best option for active dogs or those with complete ligament tears. This procedure stabilizes the knee by changing the joint's biomechanics, preventing further damage and greatly reducing the risk of degenerative joint disease. For highly active dogs, this stability is essential for maintaining long-term function and quality of life.

Myth 2 - TPLO Surgery is Only for Large Breed Dogs

A common myth we often hear is that TPLO surgery is mainly for large or giant breeds. While it's true that TPLO was initially developed for these dogs due to the biomechanical challenges their size presents, we have found it to be just as effective for small and toy breeds.

For smaller dogs, we adjust the procedure to meet their specific anatomical needs, ensuring precise results. The core principles of TPLO remain the same: restoring joint stability, reducing pain, and preventing further damage. Whether the patient is a 5-pound Chihuahua or a 100-pound Labrador Retriever, the goal is the same—helping them regain full function and enjoy a pain-free life.

Myth 3 - TPLO Surgery is Only Necessary for Show or Performance Dogs

Some pet owners mistakenly believe that TPLO surgery is only for show dogs or high-performance athletes. While these dogs do benefit from the procedure to maintain their competitive edge, the truth is that TPLO is valuable for any dog needing long-term knee stability and pain relief.

In our practice, we perform TPLO surgery on a wide range of canine patients, from household companions to working dogs. This procedure isn't about a dog's role or lifestyle; it's about ensuring they can walk, run, and play without pain. For active family pets, TPLO surgery greatly improves mobility, helping them enjoy a better quality of life well into their senior years.

Myth 4 - Recovery From TPLO is Extremely Difficult

It's natural for pet owners to worry about recovery, but we assure you that with proper care, the process is manageable and the outcomes are very positive. Most dogs start putting weight on the operated leg within a few days after surgery, and most return to nearly normal activity levels by the 12-week mark.

The recovery process follows a structured plan, including controlled activity, regular check-ups, and physical therapy if needed. During the first two weeks, we recommend strict rest to ensure the surgical site heals properly.

Gradual reintroduction of activity follows, guided by specific milestones at 4, 8, and 12 weeks after surgery. Following these protocols reduces the risk of complications and increases the success of the procedure.

In our experience, pet owners who closely follow post-operative instructions often see their dogs recover faster and with fewer challenges.

Myth 5 - TPLO Surgery Carries Significant Risks

One of the most common worries about TPLO surgery is the belief that it carries significant risks. While no surgery is completely without risk, advancements in veterinary medicine have greatly reduced complications, making TPLO surgery a safe and effective option. Improved surgical techniques, advanced tools, and strict cleanliness protocols have significantly improved outcomes for dogs.

To further reduce risks like bacterial contamination and biofilm formation, many surgeons use solutions such as Simini Protect Lavage. This innovative surgical lavage keeps the operating area clean by actively removing contaminants, reducing bacteria, and preventing complications that could slow recovery. By using these advancements, we can confidently provide safer procedures with excellent results.

Myth 6 - Postoperative Pain is Severe

It is a misconception that dogs experience severe pain after TPLO surgery. Postoperative pain is carefully managed using a multimodal approach to ensure patients remain comfortable throughout their recovery. We use a combination of pain-relief methods, including non-steroidal anti-inflammatory drugs (NSAIDs), local anesthetics, and sometimes opioids for short-term relief.

In our practice, postoperative care goes beyond just managing pain. Regular follow-ups, client education, and personalized recovery plans ensure that both the dog and their family feel supported at every stage. With these measures in place, most patients recover comfortably and return to normal activities within the expected timeframe.

Myth 7 - TPLO Surgery is Unreasonably Expensive

A common concern among pet owners is that TPLO surgery is too expensive. While the initial cost of TPLO surgery can range from $3,000 to $6,000, it's important to consider the benefits it offers for a dog's long-term mobility and quality of life. Compared to other procedures like the lateral suture technique, which may cost less initially (around $1,000 to $2,500), TPLO provides much better results, especially for active dogs or those with complete cranial cruciate ligament (CCL) tears.

The cost reflects the procedure's complexity, the surgeon's expertise, and the use of advanced tools. Unlike less durable options that may cause complications or require additional surgeries, TPLO ensures long-term joint stability, slows arthritis, and helps dogs return to an active, pain-free life. Therefore, TPLO is a cost-effective investment in your dog's health and happiness.

Proactive Steps to Ensure a Successful TPLO Surgery

Ensuring a successful outcome from TPLO surgery requires proactive steps and careful attention. Here are the key measures we recommend to pet owners:

Follow Post-Operative Care Instructions

It's crucial to follow the post-surgery care plan provided by your veterinary team. This usually includes managing your pet's activity levels, checking the surgical site for signs of infection, and attending scheduled follow-up appointments. Being consistent and attentive during recovery is essential for optimal healing.

Prevent Infections with Proper Wound Care

Preventing infections is vital for a smooth recovery. If your vet surgeon has used advanced solutions like Simini Protect Lavage during surgery, it can greatly reduce the risk of bacterial contamination and biofilm formation. At home, regularly inspect and clean the incision site as instructed by your veterinarian.

Manage the Dog’s Activity Level During Recovery

Limiting your dog’s physical activity during the first few weeks after surgery is crucial. Keep movement to short, supervised leash walks and avoid running, jumping, or climbing stairs. Gradually reintroduce activity under your veterinarian’s guidance to ensure your dog rebuilds strength safely without risking the surgical repair.

Conclusion

Misconceptions about TPLO surgery can cause unnecessary fear and hesitation, stopping dogs from getting the care they need. By addressing these myths with evidence-based facts, we aim to empower pet owners and professionals to make informed decisions.

Advancements in surgical practices have greatly improved outcomes, reducing risks and enhancing recovery. TPLO surgery continues to be a reliable and effective option for dogs of all sizes and activity levels, offering a path to a pain-free, active life. Always consult your veterinarian for personalized guidance tailored to your dog’s specific needs.