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Unilateral vs. Bilateral Medial Patellar Luxation in Dogs

Unilateral vs. Bilateral Medial Patellar Luxation in Dogs

Medial Patellar Luxation

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Owners

Compare unilateral vs. bilateral medial patellar luxation in dogs—symptoms, treatment, surgery options, and recovery differences explained simply

By 

Sustainable Vet Group

Updated on

July 17, 2026

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This article is for informational purposes only and is not a substitute for professional veterinary advice. Every case is unique, so always consult your veterinarian for guidance specific to your pet.

This content is intended for veterinary professionals for educational purposes. It does not replace clinical judgment or tailored advice. Always rely on your training, expertise, and the specific context of your patients.

Unilateral vs. Bilateral Medial Patellar Luxation in Dogs

Some dogs have MPL in one knee. Some have it in both. The presentation, the treatment, and the recovery look different depending on which situation your dog is in.

Understanding the distinction between unilateral and bilateral MPL helps you interpret your dog's symptoms correctly and know what questions to ask when your vet discusses the diagnosis and treatment plan.

 

Quick answer: Unilateral MPL affects one knee, causing the characteristic skipping gait on that leg. Bilateral MPL affects both knees, often producing a bunny-hopping gait or general rear limb stiffness rather than a clear one-sided limp. Each knee is graded independently in bilateral cases. Treatment, cost, and recovery differ based on how many knees require surgery and whether procedures are staged or done simultaneously.

 

Key takeaways

  • Unilateral MPL: One knee affected; one-sided skipping is the typical presentation.
  • Bilateral MPL: Both knees affected; bunny-hopping or general reluctance to use rear limbs is more common.
  • Each knee is graded independently in bilateral cases; grades may differ.
  • Bilateral MPL is more common in small breeds than most owners expect.
  • How laterality affects the surgery decision depends on grade, not laterality alone.
  • Cost and recovery time roughly double when both knees require surgery.

How unilateral MPL presents

In unilateral MPL, only one knee is affected. The presentation is usually clear:

  • Intermittent skipping on one specific back leg: The dog lifts the affected leg for a few steps, then resumes normal walking.
  • Occasional leg shaking or extending: The dog kicks the affected leg out to pop the kneecap back into the groove.
  • One-sided muscle atrophy: In moderate or severe cases, the thigh on the affected side becomes visibly thinner than the other.
  • A clear preference for one side: The dog consistently favors one rear leg over the other.

Unilateral MPL is easier for owners to recognize because the asymmetry is obvious. One leg skips; the other is fine.

For details on what the signs look like at each grade, see what medial patellar luxation is.

How bilateral MPL presents

Bilateral MPL often doesn't look like a knee problem at first glance. With both knees unstable, the symmetry masks the one-sided skip that makes unilateral MPL recognizable.

Common presentations in bilateral cases:

  • Bunny-hopping: The dog moves both rear legs together at speed rather than in alternating strides. This is a hallmark sign of bilateral hindlimb instability.
  • General rear end stiffness: The dog moves stiffly at the back end without a clear preference for one side.
  • Reduced activity or play: The dog seems less enthusiastic or tires more quickly than it used to, without an obvious limp to explain it.
  • Weight-shifting to the front: The dog leans forward, unloading the rear legs as much as possible during movement.

Because bilateral MPL can look like general fatigue or aging, it's worth specifically asking your vet to evaluate both knees if your dog matches any of these descriptions.

For the full symptom comparison in bilateral vs. unilateral cases, see bilateral MPL in depth.

Grading: how each knee is assessed

In both unilateral and bilateral cases, the vet grades the condition using the same 1 to 4 scale. The key difference in bilateral cases is that each knee is graded independently.

Why this matters:

  • A dog can have Grade 2 in one knee and Grade 3 in the other
  • Treatment recommendations are based on each knee's grade, not an average
  • Surgery may be appropriate for one knee but not the other, even in a bilateral case
  • The more severely affected knee typically drives the initial urgency for intervention

For the full grading explanation and what each grade means for treatment, see how each knee is graded independently.

How laterality affects the surgery decision

Whether a dog has unilateral or bilateral MPL doesn't by itself change the surgery threshold. What matters is grade.

A unilateral Grade 3 dog needs surgery on that knee. A bilateral dog with Grade 2 on one side and Grade 1 on the other may only need surgery on the higher-grade knee, or may not need surgery on either yet.

The key questions for bilateral cases:

  • What is the grade of each knee?
  • Is each knee symptomatic, or is only one causing observable problems?
  • Is the non-symptomatic knee likely to progress based on its grade and the dog's age?

When both knees are Grade 3 or 4, both typically need surgery. The decision is then whether to stage the procedures or perform them in a single session.

For the framework that guides the surgery decision for both unilateral and bilateral cases, see how laterality affects the surgery decision.

Side-by-side comparison

FactorUnilateral MPLBilateral MPL
How many knees affectedOneBoth
Typical gait presentationOne-sided skippingBunny-hopping or general stiffness
Ease of recognitionUsually obviousOften subtle; may look like fatigue
How commonLess commonMore common, especially in small breeds
Grading processSingle kneeEach knee graded independently
Number of surgeries if both need correctionOneTwo (staged or single session)
CostLowerRoughly double for bilateral surgery
Recovery period8 to 12 weeks8 to 12 weeks per surgery if staged; one extended period if single session
Support leg during recoveryUnaffected legNo reliable support leg in single-session recovery

 

Cost difference between unilateral and bilateral surgery

For a unilateral case, the cost reflects one surgical procedure, one anesthesia event, and one recovery period.

For bilateral cases requiring surgery on both knees:

  • Staged surgery: Two separate surgical fees, two anesthesia events, two sets of post-operative medication. Total cost is roughly twice the unilateral cost.
  • Single-session surgery: One anesthesia event, but both knees corrected. Some surgeons charge a reduced fee for the second knee performed in the same session. Total cost is still significantly higher than unilateral but may be lower than two completely separate staged procedures.

For specific cost estimates across both laterality scenarios, see cost difference between unilateral and bilateral surgery.

Recovery comparison

Unilateral recovery

Standard 8 to 12 week timeline. The operated leg is strictly restricted; the non-operated leg provides full support. Leash walks on an even surface, controlled exercise, and gradual reintroduction of activity.

This is the most straightforward recovery scenario. The dog has clear support on the unaffected side throughout.

Bilateral recovery (staged)

Two full 8 to 12 week recovery periods, sequenced one after the other. During the first recovery, the second knee provides support. During the second recovery, the first (now healed) knee provides support.

Total restricted activity: 16 to 24 weeks across both surgeries.

Bilateral recovery (single-session)

One recovery period of 8 to 12 weeks, but with greater demands in the early phase. Neither rear leg is fully reliable in the first week or two.

  • Hindquarter sling use during outdoor time in the first week
  • More intensive owner involvement in daily care
  • Mental stimulation through non-physical activities is important

Despite the more demanding early phase, the total recovery duration is significantly shorter than staged bilateral surgery.

For the full recovery timeline applicable to both scenarios, see how recovery differs between cases.

Frequently asked questions

How do I know if my dog has unilateral or bilateral MPL?

Your vet determines this through a physical examination of both knees. Even if only one knee is causing visible symptoms, the other should always be evaluated. Approximately 50 to 75% of dogs with MPL in one knee have concurrent or developing MPL in the other, particularly in small breeds.

If only one knee is symptomatic, should I treat both?

Not necessarily at the same time. If the non-symptomatic knee is Grade 1 or low-grade 2 with no signs of discomfort, monitoring may be appropriate. If it's Grade 3 or higher, treating both may make more sense than waiting for the second knee to become symptomatic. Discuss the specific grades and your surgeon's recommendation.

Can unilateral MPL become bilateral over time?

Yes. A dog diagnosed with unilateral MPL may develop MPL in the other knee as the condition progresses. The same genetic and anatomic factors that affected one knee are present in both. Regular evaluation of both knees allows you to detect progression in the second knee early.

Is bilateral surgery riskier than unilateral?

Published research in small dogs shows comparable complication rates between unilateral, staged bilateral, and single-session bilateral surgery. For larger dogs, staged surgery is generally preferred to reduce the recovery complexity. Your surgeon will advise based on your dog's size, health status, and grade.

Whether your dog has one affected knee or two, the treatment principles are the same: grade each knee, match the intervention to the grade, and support recovery with consistent rehabilitation. The bilateral path adds complexity, but the outcomes the research shows for dogs who go through it are strong. Most dogs with bilateral MPL who receive appropriate treatment return to full, comfortable function.

Resources

  • NIH/PMC. Comparison of complication rates: unilateral, staged, and single-session bilateral MPL surgery. pmc.ncbi.nlm.nih.gov
  • PubMed. Unilateral or single-session bilateral surgery for MPL in small dogs. pubmed.ncbi.nlm.nih.gov
  • American College of Veterinary Surgeons. Patellar Luxations. acvs.org

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