When your vet describes "how the incision was closed," they are referring to the suture pattern the specific technique used to bring wound edges together and hold them while tissue heals. Different patterns have different mechanical properties, different risks, and different appropriate indications.

This guide explains the main suture patterns used in dogs, when each is appropriate, how suture material is chosen, and what owners should know about the closure they see (or don't see) on their dog.

Quick answer: Interrupted sutures are individual stitches; if one fails, others hold. Continuous sutures run in a loop; faster but one break risks the whole line. Intradermal sutures sit beneath the skin with no external stitches required.

Key takeaways

• Simple interrupted sutures are the most common skin closure pattern; each stitch is independent
• Continuous (running) sutures close faster and distribute tension more evenly but one break risks the entire line
• Intradermal sutures are placed beneath the skin surface, providing cosmetic closure with no external sutures requiring removal
• Suture material matters: monofilament sutures carry less infection risk than braided multifilament; absorbable sutures dissolve over time; non-absorbable require removal
• Mattress sutures are used for high-tension closures where interrupted sutures would cut through tissue
• The closure pattern does not change owner responsibilities: E-collar, activity restriction, and monitoring apply regardless

Why suture pattern selection matters

SustainableVet (wound closure principles): "The role of sutures in primary wound closure is to approximate tissue edges in order to achieve a functional and cosmetically acceptable scar."

The right pattern for a given location depends on:

• Tension at the wound edges: high-tension closures need patterns that distribute force across a wider area
• Tissue type: skin, subcutaneous tissue, fascia, and internal organs each have different mechanical properties
• Location on the body: areas with movement (over joints, near the perineum) have different requirements than stable trunk locations
• Cosmetic priority: visible areas may favor intradermal patterns; perineal or axillary locations prioritize security over cosmesis
• Time constraints: running patterns are faster; interrupted patterns require more time

Interrupted suture patterns

Simple interrupted

The most commonly used technique for skin closure. Each suture is a separate unit placed, tied, and cut before the next suture is placed.

SustainableVet (interrupted vs continuous article): "Simple interrupted sutures: provide strong closure and allow precise wound edge alignment."

ScienceDirect (comparative study): "The most commonly used technique for skin closure is the simple interrupted suture pattern (SI)."

Advantages:

• If one suture fails, adjacent sutures hold the wound closed
• Individual tension adjustment at each stitch
• Easy to remove individual sutures if an infection develops at one point
• Precise edge-to-edge alignment

Disadvantages:

• More time-consuming than continuous patterns
• More suture knots, each of which is a potential tissue reaction site

Horizontal mattress sutures

The suture passes through tissue on one side, crosses horizontally, passes through the other side, returns, and is tied creating a rectangular pattern that bridges the wound.

SustainableVet: "Cruciate sutures: crossed pattern sutures that distribute tension evenly and reduce skin edge inversion, improving healing."

When used: high-tension closures where standard interrupted sutures would cause tissue necrosis from excessive focal pressure; also used when wound edges tend to invert (fold inward).

Disadvantages: can compromise blood supply to the wound edge if tied too tightly; should not be the primary pattern for routine low-tension skin closure.

Vertical mattress sutures

Similar to horizontal mattress but the loop goes through tissue at two depths one deep bite and one superficial bite on each side. Particularly good at everting (turning outward) wound edges, which promotes primary healing.

Continuous suture patterns

Simple continuous (running)

A single suture is placed from one end of the wound to the other in a running pattern, tied at each end.

SustainableVet: "Continuous sutures: faster to place and distribute tension evenly but risk wound opening if one suture breaks."

SustainableVet (wound closure principles): "Continuous sutures role: Running stitches provide quick closure and distribute tension evenly, reducing tissue trauma."

Advantages:

• Significantly faster than placing individual interrupted sutures
• More even tension distribution along the wound length
• Fewer knots overall

Disadvantages: A failure at any point in the line (suture breakage, knot failure) can lead to the entire closure unzipping. For this reason, simple continuous patterns are less common for primary skin closure where security is paramount.

Ford interlocking (locking continuous)

A variation of the continuous pattern where each bite is locked before proceeding. This prevents the entire line from running if one segment fails each segment is anchored.

When used: closure of fascia and body wall where a running pattern's speed advantage is important but security is still needed.

Intradermal (subcuticular) suture

The most cosmetically appealing closure technique. The suture is placed within the dermis (the layer just beneath the outer epidermis), running horizontally from one end of the wound to the other without penetrating the skin surface.

SustainableVet (intradermal closure article): "Hidden sutures: sutures are placed beneath the skin surface, preventing your dog from licking or scratching them, which promotes safer healing. Cosmetic benefit: intradermal closure results in less visible scarring compared to traditional external stitches. Reduced suture removal: because sutures are buried, they often do not require removal."

ScienceDirect (comparative study): "The continuous intradermal suture pattern (ID) has been lately popularized as a superior method of cosmetic skin closure. It is generally assumed that the intradermal suture pattern has superior cosmetic results, mainly because the epidermis is not penetrated and therefore inflammation is minimal, and a fine approximation of wound edges can be achieved, resulting in minimal scarring."

Suture material used: absorbable monofilament (poliglecaprone 25 or polidioxanone) in a fine gauge (3/0 or 4/0). ScienceDirect: "Intradermal pattern with 4/0 poliglecaprone 25 was superior in terms of cosmetic, clinical, and histologic appearance compared to simple interrupted pattern."

Disadvantages: requires more surgical skill to execute correctly; not appropriate for contaminated wounds or locations where wound tension is high.

Suture material: what it means for healing

Absorbable vs. non-absorbable

Absorbable sutures dissolve over time through hydrolysis (synthetic) or enzymatic digestion (natural materials). They are used for internal layers (subcutaneous tissue, fascia, body wall, internal organs) and for intradermal skin closure. No removal required.

SustainableVet (subcutaneous closure article): "Absorbable sutures like polyglycolic acid are preferred for internal layers to avoid the need for suture removal and reduce irritation risk."

Non-absorbable sutures remain in place indefinitely unless removed. Used for skin closure when suture removal at 10 to 14 days is planned. Examples: nylon (monofilament), polypropylene, polyester.

Monofilament vs. multifilament

Monofilament sutures are single-strand; they move through tissue smoothly and have minimal surface area for bacteria to adhere to.

SustainableVet (wound closure principles): "Monofilament sutures reduce infection risk due to less bacterial trapping compared to braided multifilament sutures."

Multifilament (braided) sutures are stronger and easier to handle but have a greater surface area where bacteria can colonize and form biofilm. For this reason, braided sutures are generally avoided for skin closure of contaminated or infection-prone wounds.

Tissue layers and closure sequence

Most surgical wounds are closed in layers, not just at the skin surface. A typical soft tissue closure:

1. Deep layer (fascia or body wall): absorbable suture in a continuous or simple interrupted pattern
2. Subcutaneous layer: absorbable suture, often continuous; this eliminates dead space where fluid collects and bacteria proliferate
3. Skin: interrupted or intradermal with absorbable (for intradermal) or non-absorbable (for interrupted with planned removal)

SustainableVet (subcutaneous closure): "The subcutaneous tissue is closed first to reduce dead space, followed by skin closure to protect the wound from contamination."

Closing dead space is critical. Dead space is the empty volume left when tissue layers are not approximated it fills with serum, creating a perfect environment for bacterial growth and seroma formation.

What this means for owners

The suture pattern does not change the owner's responsibilities:

• E-collar compliance is required regardless of whether external stitches are visible
• Activity restriction applies regardless of pattern
• Wound monitoring (twice daily, with photographs) is required regardless of pattern

If your dog has an intradermal closure, there are no external sutures to count or check but you still look at the incision line itself for signs of infection or dehiscence.

For the wound care protocol, see wound care after surgery. For signs of complications including wound breakdown, see signs of complications after soft tissue surgery. For the SSI prevention context, see how to prevent surgical site infections in dogs.

Frequently asked questions

My dog has no visible stitches. Is the wound still closed?

Yes. Intradermal or subcuticular closure places sutures beneath the skin surface. The wound is closed; no external sutures are visible. The E-collar is still required, and the wound still needs daily monitoring.

Do intradermal sutures need to be removed?

Not typically. Absorbable intradermal sutures dissolve over 60 to 90 days without requiring a suture removal appointment. If non-absorbable material was used intradermally, your vet will advise on removal.

My dog's sutures look red around the knots. Is that infection?

Mild redness around suture entry points in the first 3 to 5 days is a normal tissue reaction. Yellow or green discharge, redness spreading beyond the knot area, or warmth after day 5 are signs of infection.

What happens if one suture falls out?

For simple interrupted patterns, losing one suture does not typically compromise the closure if wound edges remain apposed. Contact the vet to assess whether replacement is needed. For continuous patterns, any suture failure warrants same-day veterinary assessment.

Why are some incisions closed with staples instead of sutures?

Staples provide fast, secure closure used in orthopedic cases where speed and high tension matter. SustainableVet: "Staples: quick to apply but may cause more skin irritation and require removal after healing."

My dog had internal sutures placed. Can I feel them under the skin?

Absorbable internal sutures are sometimes palpable as small firm knots under the skin, particularly in lean dogs. This is normal and not a sign of complication; they dissolve over 60 to 90 days.

Resources

• SustainableVet. Interrupted vs. Continuous Suturing in Dogs. sustainablevet.org
• SustainableVet. Intradermal Closure in Dogs: Techniques and Benefits. sustainablevet.org
• ScienceDirect. Comparison of Continuous Intradermal with Simple Interrupted Suture Pattern in Dogs. sciencedirect.com
• SustainableVet. Subcutaneous Closure Techniques in Dogs. sustainablevet.org
• SustainableVet. Principles of Wound Closure in Veterinary Surgery. sustainablevet.org

Not every wound can be closed with sutures. Not every wound should be.

When a wound is too large, too infected, or has lost too much tissue to close edge to edge, the body uses a different route: secondary intention healing, where the wound fills in from the bottom up, without surgical closure.

For owners managing a dog or cat through this process, understanding what is supposed to happen at each stage makes the difference between appropriate monitoring and unnecessary alarm.

Quick answer: Secondary intention healing is the process by which open wounds heal without surgical closure. The wound fills with granulation tissue from the base, contracts inward from the edges, and is covered by new epithelium from the margins inward. It is slower than primary (sutured) healing, requires more intensive home care, and takes longer in cats than in dogs. Most wounds appropriate for secondary intention healing do close, though the timeline varies significantly by wound size, location, and the animal's health.

Key takeaways

• Secondary intention healing applies when wounds cannot or should not be sutured: Too infected, too large, too much tissue loss, or dehisced wounds that cannot be re-closed.
• The wound heals from the base up: Granulation tissue fills the wound bed before the surface closes.
• Wound contraction is the primary closure mechanism: In most cases, the wound shrinks significantly through contraction before epithelium covers the remaining area.
• Cats heal more slowly than dogs by secondary intention: They produce less granulation tissue and contract wounds more slowly.
• Active open wound management is required: The wound cannot simply be left alone. Regular cleaning, dressing changes, and monitoring are essential throughout.
• Infection monitoring is critical: An open wound has ongoing exposure to bacteria. Recognizing infection in a wound being managed by secondary intention is a core owner skill.

Primary vs. secondary intention healing: the key distinction

Primary intention healing occurs when wound edges are brought together by sutures, staples, or tissue glue. A spay incision is the classic example. The two edges bond, and the wound heals across the margin rather than filling in.

Secondary intention healing occurs when the wound is left open. The wound heals by:

1. Filling from the base with granulation tissue
2. Contracting inward as myofibroblasts (specialized cells) pull the wound edges toward each other
3. Epithelializing as new skin cells migrate from the wound margin inward to cover the contracted wound surface

Primary healing takes days to two weeks for a clean surgical incision. Secondary intention healing takes weeks to months, depending on wound size and individual factors.

When secondary intention is chosen or necessary:

• The wound is too infected to close safely: suturing an infected wound traps bacteria and nearly always leads to dehiscence
• Too much tissue has been lost for primary closure without excessive tension
• The wound has already dehisced and the tissue is not in a suitable state for re-suturing
• The wound location or anatomy makes primary closure technically difficult
• The wound is a bite wound with deep contamination that requires ongoing drainage

The stages of secondary intention healing

Stage 1: Inflammation and debridement

The same initial response as any wound: blood vessels dilate, white blood cells flood the area, and the immune system begins clearing bacteria and dead tissue.

In an open wound undergoing secondary intention healing, this stage is extended compared to a sutured incision because there is no skin surface to protect the wound from the environment. Bacteria continue to contact the wound throughout healing, which is why open wound management with appropriate dressings is essential from day one.

What you see: The wound bed looks red, moist, and may have discharge. Some tissue may appear necrotic (dark, brown, or black) early on and will be cleared through debridement.

Stage 2: Granulation tissue formation

This is the most visible and distinctive stage of secondary intention healing.

Granulation tissue is a specialized tissue composed of new blood vessels, fibroblasts, and collagen. It fills the wound bed from the base upward, gradually reducing the depth of the wound.

What healthy granulation tissue looks like:

• Bright red or deep pink color
• Slightly bumpy or granular surface texture (which gives the tissue its name)
• Moist appearance
• Bleeds easily when touched, which is normal

What unhealthy granulation tissue looks like:

• Pale, grey, or brown: suggests insufficient blood supply or ongoing infection
• Excessive height above wound margin (proud flesh or exuberant granulation): overgrown tissue that blocks epithelialization, more common in horses but can occur in dogs and cats, particularly on legs
• Sloughing or detaching tissue: suggests active infection

For how infection affects the healing timeline in wounds undergoing secondary intention healing, including how to recognize when a granulating wound has become secondarily infected, that guide covers the stage-by-stage signs.

Stage 3: Wound contraction

As granulation tissue fills the wound bed, specialized cells called myofibroblasts begin contracting the wound from the edges inward.

Wound contraction is the most powerful closure mechanism in secondary intention healing. In trunk and body wounds, contraction can close a large proportion of the wound area before epithelialization is needed.

Limb wounds contract less efficiently than trunk wounds. The skin on legs has less mobility and elasticity than trunk skin, which limits how much the wound can contract. Wounds approaching or exceeding 50% of the limb circumference may require reconstructive surgery (skin graft or flap) if secondary intention healing stalls.

What you see: The wound visibly shrinks in size from day to day and week to week. The margins move inward. This is the most encouraging phase to observe as an owner.

Stage 4: Epithelialization and maturation

As the wound contracts and the granulation bed reaches near-surface level, new epithelial cells migrate from the wound margins inward, covering the remaining wound surface.

Epithelialization produces new skin that initially appears thin, pale, and fragile compared to normal skin. Over weeks to months, the new skin thickens and gains pigmentation.

What you see: A thin, pale or pinkish skin surface covering the wound, initially fragile and easily disrupted. The wound area will be hairless initially. Some permanent hair loss may remain over scarred tissue.

Cats vs. dogs in secondary intention healing

Cats and dogs differ measurably in how they heal open wounds, and these differences affect management decisions and owner expectations.

Research on open cutaneous wound healing found that cats produced significantly less granulation tissue than dogs, with a peripheral rather than central distribution pattern. Epithelialization and total wound closure were slower in cats across the 21-day measurement period.

In practical terms: if your cat is healing by secondary intention, the process takes longer than it would for a dog with an equivalent wound. Extended bandage change schedules, longer monitoring periods, and more patience are required.

For secondary healing in cat surgical wounds specifically, including how secondary intention becomes the management pathway after dehiscence, that guide covers the transition from sutured wound to open wound management in the feline context.

Home care during secondary intention healing

Managing a wound healing by secondary intention at home requires consistent daily attention.

Bandage and dressing changes

Your veterinarian will prescribe a dressing protocol appropriate to the wound stage. This typically involves:

• Wet-to-dry dressings in early stages: Saline-moistened gauze that, when removed, mechanically debrides the wound surface
• Non-adherent moist dressings in the granulation phase: Protect the forming granulation tissue without disrupting it on removal
• Transition to protective dressings in the epithelialization phase: Protect fragile new epithelium from trauma and contamination

Dressing changes are typically daily during active wound stages, reducing in frequency as healing progresses. Follow your veterinarian's specific schedule.

Cleaning

Clean the wound with saline or a vet-approved wound wash at each dressing change. Do not use hydrogen peroxide, alcohol, or undiluted iodine, which damage the fragile cells forming in the wound bed.

Gentle irrigation with saline via syringe under mild pressure is more effective than dabbing or swabbing.

Infection monitoring

An open wound has ongoing bacterial exposure. Infection monitoring during secondary intention healing is a consistent, ongoing responsibility.

For identifying infection in wounds healing by secondary intention, including how the signs of infection in an already-open wound differ from signs of infection in a sutured wound, that guide covers the identification markers clearly.

Signs that an open wound has become infected or that existing infection has worsened:

• Wound bed tissue changing from bright red to pale, grey, or dark
• Discharge changing from clear or serosanguineous to purulent (yellow, green, thick)
• Foul or unusual odor from the wound
• Surrounding skin becoming increasingly red or warm
• Your dog or cat becoming lethargic, reduced appetite, or feverish

Licking prevention

Open wounds require continuous licking prevention, just as sutured wounds do. An open wound is, if anything, more accessible and more tempting to the animal.

E-collar or recovery suit use throughout the full secondary intention healing period is essential. The healing window for secondary intention is weeks to months, not days.

For context on wounds that progress to secondary healing from the perspective of what dehiscence means for the wound management plan, that guide explains the pathway from surgical wound to open wound management.

When secondary intention healing needs veterinary reassessment

Contact your vet if:

• The wound is not visibly progressing (shrinking, filling) over two to three weeks
• The granulation tissue is pale, sloughing, or growing above the wound margin level
• Discharge is increasing in volume or changing from clear to purulent
• You see signs of systemic illness alongside the wound changes
• The wound reopens or enlarges rather than contracting

Some wounds, particularly on limbs, stall during secondary intention healing and require surgical intervention to close. Even wounds that stall can usually be surgically closed once the wound bed is clean, because secondary intention healing will have reduced the wound area considerably, making reconstruction simpler.

Frequently asked questions

How long does secondary intention healing take in dogs?

Timeline depends entirely on wound size, location, depth, the animal's health, and whether infection is present. Small wounds may close in two to four weeks. Large wounds, particularly on limbs, can take months. Your veterinarian will give you expectations specific to your dog's wound.

Is secondary intention healing painful?

Open wounds involve ongoing tissue exposure and regular dressing changes, both of which can be uncomfortable. Pain management is typically addressed by your veterinarian with appropriate medications during active healing phases. Dressing changes should be done gently, and your vet can advise on whether sedation for wound care is appropriate in particularly painful cases.

Can a wound be closed surgically after starting secondary intention healing?

Yes, often. Secondary intention healing can reduce a large wound to a smaller, surgically manageable size. Once granulation tissue is healthy and the wound is free of infection, reconstruction surgery, such as a skin flap or graft, can close what remains. This is a common approach for large wounds.

Do secondary intention wounds leave more scarring than sutured wounds?

Yes. Open wound healing produces more scar tissue than sutured primary closure, and the scar covers a larger area. Hair may not regrow over the scar tissue. However, most secondary intention healed wounds in dogs and cats are functionally excellent even if cosmetically less ideal.

Can secondary intention healing become infected?

Yes, and this is one of the primary concerns during the healing period. An open wound has ongoing bacterial exposure at every dressing change and during any gap in barrier protection. Consistent cleaning protocol, appropriate dressings, and licking prevention minimize infection risk, but monitoring throughout healing is essential.

Secondary intention healing is slower and demands more from owners than sutured wound management. But it is also a genuinely effective biological process that closes wounds that could not be closed any other way. Understanding what each stage looks like, and what deviations from normal look like, transforms home wound management from anxiety-inducing to systematic.

Resources

The following sources were used as reference and background for this article:

• MSPCA-Angell. 2nd Intention Healing in Full-Thickness Skin Wound Management, Revisited. mspca.org
• Veterinary Partner (VIN). Wound Healing in Dogs and Cats. veterinarypartner.vin.com
• Bohling, M.W. et al. Cutaneous wound healing in the cat: a macroscopic description and comparison with cutaneous wound healing in the dog. Veterinary Surgery. pubmed.ncbi.nlm.nih.gov
• Today's Veterinary Practice. Moist Wound Healing: The New Standard of Care. todaysveterinarypractice.com
• DVM360. Basic Principles of Wound Management. dvm360.com
• Vetrix. 7 Steps of Effective Veterinary Wound Management. rethinkhealing.com

Suture material selection is one of the first decisions made in surgical planning, and it is more nuanced than "this one dissolves, this one doesn't."

The right material for each layer of tissue depends on how long that layer needs support, whether the wound is clean or contaminated, how thick the tissue is, and what the patient's body will tolerate without excessive reaction.

Quick answer: For dogs: PDS (polydioxanone) is the preferred absorbable monofilament for deep structural layers (linea alba, fascia) because of its long strength retention; Monocryl (poliglecaprone 25) for subcutaneous closure because of minimal tissue reaction; Vicryl (polyglactin 910) where braided handling properties are preferred over monofilament; nylon or Prolene for external skin sutures. Monofilament materials are preferred in contaminated wounds or high-infection-risk cases.

Key takeaways

• PDS retains strength for 4 to 6 weeks, making it the standard for slow-healing structural layers.
• Monocryl absorbs in 90 to 119 days with minimal tissue reaction, ideal for subcutaneous closure.
• Vicryl is braided, offering better handling and knot security but higher infection risk in contaminated fields.
• Monofilament sutures carry lower infection risk because their smooth surface resists bacterial adhesion.
• Nylon loses only 30% tensile strength in 2 years, making it reliable for external skin sutures needing removal.
• Silk and catgut are largely obsolete in modern small animal surgery due to high tissue reaction.

The decision framework: what each layer needs

Every tissue layer in canine surgery has different mechanical requirements and healing timelines. The suture material must match both.

Absorbable materials: which to use and when

PDS (polydioxanone)

Absorbable monofilament. The most commonly used material for structural layers in canine surgery.

Properties (Clinician's Brief, 2012): "Polydioxanone and polyglyconate are slow to absorb." PDS retains approximately 70% of its tensile strength at 2 weeks and 50% at 4 to 6 weeks. Full absorption at 180 to 210 days.

Best for: linea alba, fascia, deep muscle closure, joint capsule in orthopedic surgery, any layer that requires holding strength through 4 to 6 weeks of healing.

Drawback: high "memory" (returns to original shape if kinked), which makes handling slightly less smooth than braided alternatives.

For how PDS compares in fascial closure specifically, see absorbable sutures used in muscle closure.

Monocryl (poliglecaprone 25)

Absorbable monofilament. The preferred subcutaneous and intradermal suture in most canine procedures.

Clinician's Brief: "Poliglecaprone 25 is a rapidly absorbable suture. In the first week, it loses 40 to 50% of its tensile strength and 100% at 21 days postimplantation. This rapid absorption makes it a good choice for rapidly healing tissue, such as subcutaneous and urinary bladder tissue."

Best for: subcutaneous closure, intradermal skin closure, urinary bladder closure.

Important limitation: Clinician's Brief explicitly states Monocryl "is a poor choice for tissue that is slow to regain tensile strength, such as fascia (linea alba) or tendons." Do not use it for structural layers.

Vicryl (polyglactin 910)

Absorbable multifilament (braided). Maintains strength for approximately 2 to 3 weeks and absorbs by 56 to 70 days.

Best for: subcutaneous tissue closure, vessel ligation, subcutaneous fat layer in medium-duration support applications.

Trade-off: braided structure provides excellent knot security and pliability (easier handling than monofilaments), but the interstices between strands can harbor bacteria. In clean elective surgery, this is acceptable. In contaminated wounds, monofilament is preferred.

Clinician's Brief: "Polyglactin 910 and polyglycolic acid are soft, pliable, and easy to handle. These sutures are appropriate for vessel ligation and subcutaneous tissue closure."

Not recommended for: urinary bladder closure (may lose strength prematurely in alkaline urine environment) or contaminated wounds.

For how Vicryl compares within the monofilament vs. multifilament decision, see monofilament vs multifilament decision. For the equivalent material guide for cats, see suture material selection in cats for comparison.

Non-absorbable materials: which to use and when

Nylon (polyamide)

Monofilament non-absorbable. The most common skin closure suture in veterinary surgery.

Properties: "Monofilament nylon degrades slowly; it loses only 30% of its tensile strength in 2 years. The monofilament suture is noncapillary and inexpensive and causes minimal tissue reaction." (Clinician's Brief)

Drawbacks: poor knot security relative to braided materials (requires 4 to 5 throws for a secure knot) and high memory.

Best for: external skin sutures requiring removal at 10 to 14 days, where low tissue reaction and cost efficiency matter.

Prolene (polypropylene)

Monofilament non-absorbable. Very similar to nylon in application but maintains strength indefinitely without any degradation.

Best for: cardiovascular tissue, permanent repairs where long-term structural support is required, and intradermal skin closure in wounds under tension where prolonged support is desired.

Silk

Multifilament non-absorbable (technically loses strength over about a year, but is functionally non-absorbable). Offers excellent knot security and the easiest handling of any suture material.

Important limitation: silk has the highest tissue reaction of any suture material. Modern veterinary surgery has largely replaced it with synthetic materials. Appropriate for securing drains or retracting tissues, not for wound closure.

For the full absorbable vs. non-absorbable framework, see absorbable vs non-absorbable suture decision.

Monofilament vs. braided: the infection risk trade-off

The practical difference between monofilament and braided materials becomes significant in two situations: contaminated wounds, and wounds in high-risk patients.

Monofilament advantage: smooth surface resists bacterial adhesion. Bacteria cannot colonize the interstices between strands because there are none.

Multifilament disadvantage: the "wicking" effect braided interstices can draw fluid and bacteria from the wound surface through the suture strand by capillary action.

In clean elective surgery, either type is acceptable with appropriate technique. In contaminated wounds, bite wounds, or patients with immune compromise, monofilament is the safer choice for every layer.

For how material type affects infection risk within the closure decision, see how tissue type influences material choice.

Suture size alongside material: a reminder

Size and material are separate decisions. The right material in the wrong size creates problems. For a dog's linea alba:

• Right material (PDS), wrong size (3-0 in a 30 kg dog) = inadequate tensile strength, risk of hernia
• Right material (PDS), right size (0 or 2-0) = appropriate support through healing

For the complete suture size selection guide, see suture size alongside material selection. For needle selection alongside suture material, see needle selection alongside suture material.

Materials to avoid in dogs

Chromic catgut: natural, unpredictable absorption, higher inflammatory response than synthetic alternatives. Replaced by synthetic absorbable sutures in modern practice.

Silk for wound closure: high tissue reactivity; may cause chronic sinus tracts if buried. Acceptable only for drain fixation or similar temporary use.

Non-absorbable sutures in internal layers: sutures that cannot be retrieved if a problem develops create a permanent foreign body. Use absorbable materials for all buried layers.

Frequently asked questions

My dog had surgery with Vicryl for internal layers and nylon for skin. Is that a standard combination?

Yes, entirely standard. Vicryl for subcutaneous closure and nylon for external skin is one of the most common material combinations in routine canine soft tissue surgery. Vicryl's knot security and handling properties make it well-suited to the subcutaneous layer, and nylon for skin allows easy, visible monitoring and clean removal at 10 to 14 days.

Why did the vet use PDS for some layers and Monocryl for others in the same surgery?

Because those layers have different healing timelines and different structural requirements. The linea alba takes 4 to 6 weeks to regain strength and needs PDS. The subcutaneous tissue heals in 2 to 3 weeks and needs only Monocryl. Using PDS everywhere would be more material than the subcutaneous layer requires; using Monocryl on the linea alba would leave the structural closure without support before healing is complete.

Does suture material matter for my dog's recovery experience?

Yes, indirectly. Larger or more reactive materials in internal layers produce more post-operative inflammation, which causes more discomfort. Monofilament materials in contaminated sites reduce infection risk. Absorbable intradermal closure eliminates the licking target and removal visit. All of these affect how comfortable and smooth your dog's recovery is.

Suture material selection in dogs is a matching exercise: match the material's properties to the tissue's needs at each layer. PDS for long-healing structural layers. Monocryl for fast-healing supportive layers. Monofilament for contaminated environments. The right answer at every layer is the smallest, most appropriate material that holds through the tissue's healing timeline without unnecessary reaction.

Resources

• Clinician's Brief. How to Fine-Tune Suture Choices for Today's Veterinarian. cliniciansbrief.com
• WSAVA 2016 (VIN). Suture Materials. vin.com
• Veterinary Practice News. What Suture Size Should I Use? veterinarypracticenews.com
• Veterian Key. Selection of Suture Materials, Suture Patterns, and Drains. veteriankey.com

Dog neuter surgery is one of the most common veterinary procedures in the US. The surgical technique itself takes minutes once you know what you are doing. But the closure decisions which approach, which layers, which materials matter significantly for recovery.

Understanding what your vet did and why helps you care for your dog appropriately during healing and recognize when something needs attention.

Quick answer: Dog neuter closure depends on the incision approach. The prescrotal approach uses a three-layer closure: subcutaneous tissue, subcutaneous fat, and skin. The scrotal approach typically does not require full closure the scrotal skin is inverted or left partially open, and only a single dartos fascia suture may be placed. Absorbable sutures are standard for internal layers; skin may use absorbable or non-absorbable depending on surgeon preference.

Key takeaways

• Two main approaches exist: prescrotal (standard) and scrotal, each with different closure requirements.
• Prescrotal approach requires three-layer closure: tunica/subcutaneous layers and skin.
• Scrotal approach does not require full suturing the scrotum is inverted or left open.
• Absorbable monofilament sutures (Monocryl or PDS) are standard for internal layers.
• Intradermal closure is commonly used for skin to reduce self-trauma and eliminate removal visits.
• Scrotal hematoma is the most common complication and is often related to technique or over-activity post-op.

Two approaches, two different closure decisions

Prescrotal approach (traditional)

The incision is made in the skin just in front of the scrotum (the prescrotal area). The testicles are pushed forward through this incision one at a time.

Why prescrotal:

• Standard in most private practice settings
• Allows a clean, anatomically clear incision that is away from the scrotal skin
• Required for cryptorchid dogs where retained testicles need to be located

Prescrotal closure three layers:

1. Tunica vaginalis or subcutaneous fascia (where opened): closed with absorbable suture
2. Subcutaneous fat: closed with 2-0 or 3-0 absorbable suture (Monocryl or Vicryl) in a continuous or interrupted pattern
3. Skin: closed with intradermal absorbable suture, interrupted nylon, or skin staples

Today's Veterinary Practice notes: "Prescrotal incisions for dogs should always be closed by appropriate tissue apposition with buried absorbable suture."

The University of Edinburgh (CNR Good Practice Guide) confirms: "With the pre-scrotal approach, a standard three-layer closure should be performed."

Scrotal approach (increasingly adopted)

The incision is made directly on the scrotum over each testicle. Two small incisions are made one per testicle rather than one prescrotal incision.

Why scrotal:

• Shorter surgical time
• Less suture material needed
• Reduced scrotal hematoma risk
• No risk of accidental urethral injury
• Lower complication rate reported vs. prescrotal in published studies

Scrotal closure minimal:

Clinician's Brief (2016) states explicitly: "Do not attempt to fully close the dartos fascia, intradermal, and/or cutaneous layers of the incision with sutures, as this can lead to discomfort, seroma formation, self-trauma, and postoperative complications."

For the scrotal approach, the scrotum is inverted and left to heal by second intention. A single interrupted suture may be placed in the dartos fascia to reduce the size of the opening. Small amounts of drainage from the scrotal wound in the first 24 to 48 hours are normal.

For comparison with the neuter closure protocol in cats, see neuter closure in cats for comparison.

Suture materials for prescrotal closure

A published randomized controlled trial (PMC11047773) comparing smooth monofilament suture to barbed suture in canine spay/neuter three-layer continuous closure found barbed suture reduced average closure time from 6.5 minutes to 4.9 minutes while maintaining equivalent wound outcomes. Barbed sutures are increasingly used in high-volume spay/neuter clinics for this reason.

For the general closure protocol context that this procedure follows, see general surgical closure protocol.

Closed vs open castration technique

Within either incision approach, the surgeon also chooses between closed and open castration technique:

Closed castration: the parietal tunica vaginalis is left intact. The fascial layers are stripped from the spermatic cord to exteriorize the testicle without opening the tunic. The cord is ligated and transected. Less risk of scrotal hematoma because the tunic containing the cord is never opened.

Open castration: the parietal tunica is incised to expose the vas deferens and vessels separately. Preferred for larger dogs where a single mass ligature might be inadequate. Requires closure of the tunica if opened.

DVM360 documented closed castration using 2-0 Vicryl for the spermatic cord ligature. Both techniques are acceptable; most surgeons use closed castration as their default.

Layered closure principles applied here

Neuter surgery closure follows the same principles as all layered closure in small animal surgery. For the underlying framework, see layered technique applied in neuter closure.

For suture removal timing after neuter surgery, see suture removal after neuter surgery. For a closure checklist applicable to this procedure, see checklist for neuter closure.

Post-operative care for owners

What is normal after neuter closure:

• Mild swelling in the scrotal area for 2 to 5 days
• Slight redness at the skin edge for 3 to 5 days
• Small amount of bloody drainage from the scrotal approach wound in the first 24 hours
• Some licking attempts at the incision area

What needs a vet call:

• Scrotal swelling growing larger after the first 48 hours (possible hematoma)
• Yellow or green discharge
• Wound opening
• Dog unable to urinate or straining

E-collar is non-negotiable. Self-trauma to a neuter incision can cause wound dehiscence within hours. Even dogs that have never licked wounds before will target a fresh incision. Keep it on until your vet clears removal.

Activity restriction:

• Leash walks only for 10 to 14 days
• No running, jumping, or rough play
• No access to water (swimming, puddles) until the wound is healed

Frequently asked questions

My dog had the scrotal approach and the wound looks open. Is that normal?

Yes, if your vet used the scrotal approach. The small openings are intentionally left to heal on their own. Some discharge and minor swelling are expected. Monitor daily and contact your vet if swelling is increasing after day 3, if the discharge becomes yellow or foul-smelling, or if the dog is in obvious discomfort.

When can my dog go back to full activity after neuter surgery?

Ten to 14 days of restriction is standard. After the prescrotal approach, full internal healing takes longer than external skin healing. Early activity is the most common cause of scrotal hematoma and incision complications after dog neuter surgery.

Can my dog get wet after neuter surgery?

No, until the wound is fully healed and your vet clears it. Water softens the suture line, promotes bacterial growth, and can cause wound breakdown. This includes puddles on walks keep your dog away from wet surfaces during the restriction period.

Dog neuter closure looks simple because the surgery is routine. The technique behind it the approach selection, the tissue layers closed, the suture material matched to each layer reflects the same precision applied to any surgical wound. When the closure is done correctly and the dog rests properly, neuter surgery heals quickly and without complication.

Resources

• Today's Veterinary Practice. Update on Orchiectomy Techniques for Dogs and Cats. todaysveterinarypractice.com
• Clinician's Brief. Scrotal Approach to Canine Orchiectomy: Step-by-Step Guide. cliniciansbrief.com
• DVM360. Scrotal Castration versus Prescrotal Castration in Dogs. dvm360.com
• PMC. Randomized trial comparing barbed suture vs smooth monofilament in canine closure. 2024. ncbi.nlm.nih.gov

When your dog or cat has surgery, sutures are doing different jobs in different layers of the body. Some need to stay permanently. Others should dissolve quietly on their own. The decision between absorbable and non-absorbable isn't a preference: it follows a logical set of rules based on what each layer of tissue needs.

Understanding the difference helps you know what your vet placed, whether a recheck visit is needed, and what to watch for during healing.

Quick answer: Absorbable sutures dissolve through hydrolysis over weeks to months and are used for internal tissue layers (muscle, fascia, subcutaneous tissue). Non-absorbable sutures resist breakdown and are used for skin closure (requiring removal) or long-term structural repairs like ligament reconstruction. The material, pattern, and placement location determine which type is correct for each situation.

Key takeaways

• Absorbable sutures dissolve on their own and are used for internal layers in nearly all soft tissue surgery.
• Non-absorbable sutures do not break down and either need removal or remain permanently in place.
• PDS (polydioxanone) and Monocryl (poliglecaprone) are the most common absorbable materials in small animal surgery.
• Nylon and polypropylene are the most common non-absorbable materials for skin closure.
• No removal is needed for absorbable skin sutures, reducing recheck visits for many patients.
• Multifilament sutures carry higher infection risk than monofilament in contaminated wound environments.

How absorbable sutures work

Absorbable sutures break down through hydrolysis. Water penetrates the suture filaments and causes the polymer chains to dissolve. This happens over a predictable timeline that varies by material.

The WSAVA 2016 Suture Materials review describes the ideal absorbable suture: "pliable, sterile, with uniform tensile strength, non-inflammatory, degrading at just the right time, strong enough to support the repair."

The key word is timing. The suture must maintain strength long enough for the tissue to heal, then disappear without causing a foreign body reaction.

Common absorbable suture materials in veterinary surgery

Key distinction: Monocryl and PDS are monofilament (single strand). Vicryl is multifilament (braided). Monofilament materials cause less tissue drag and lower infection risk than braided materials in contaminated environments.

Chromic catgut is rarely used today in small animal surgery due to its unpredictable absorption and inflammatory response. Synthetic materials have replaced it in most veterinary contexts.

Common non-absorbable suture materials

Veterian Key (Surgery of the Abdominal Cavity) specifically cautions: "Monofilament, nonabsorbable suture material (polybutester, polypropylene, nylon) has been associated with suture sinus formation and should be avoided" in continuous abdominal wall patterns. Non-absorbable materials belong at the skin surface, not in deep tissue layers.

For how material choice affects infection risk at the wound site, see infection risk differences between absorbable and non-absorbable.

Where each type is used by tissue layer

The University of Saskatchewan WCVM Lab notes: "For skin sutures (simple interrupted or cruciate), a monofilament nonabsorbable material (polypropylene, polybutester, or nylon) is a good choice."

For material selection in dog-specific procedures, see material selection for dog surgery. For cat-specific decisions, see material selection for cat surgery.

Monofilament vs multifilament within each category

Both absorbable and non-absorbable sutures come in monofilament and multifilament forms. This distinction matters as much as absorbable vs. non-absorbable in infection-prone environments.

• Monofilament: single strand, smooth surface, less bacterial wicking, lower tissue drag
• Multifilament (braided): multiple strands twisted or braided together, stronger handling properties, higher infection risk in contaminated fields

In clean elective surgery, either may be appropriate. In contaminated wounds, bite wounds, or infection-prone cases, monofilament is preferred.

For a full comparison of monofilament vs. multifilament properties, see monofilament vs multifilament alongside absorbable vs non-absorbable.

Non-absorbable sutures: when removal is and isn't needed

Requires removal (10 to 14 days):

• External skin sutures placed using nylon, Prolene, or other non-absorbable materials
• Your vet will clip and pull each suture individually using suture scissors or a seam ripper

Does not require removal:

• Non-absorbable sutures used internally for permanent structural repairs (ligament reconstruction, vascular procedures) remain in place indefinitely

Absorbable skin sutures:

• Used when the surgeon places an intradermal or buried closure
• No removal needed; the material dissolves on its own

For timing of non-absorbable skin suture removal in dogs, see when non-absorbable sutures need removal in dogs. For cats, see when non-absorbable sutures need removal in cats.

What this means for your pet's recovery

Understanding suture type helps you know what to expect at home:

• No visible sutures = intradermal absorbable closure. No removal needed. Monitor for swelling or separation.
• Visible sutures = external closure. A recheck is scheduled for removal at 10 to 14 days. Do not try to remove them yourself.
• All internal sutures dissolve. You will never see or feel them surface through the skin in normal healing.
• A small firm lump along the incision can be a suture knot reacting as it absorbs. This is common with Vicryl in cats and usually resolves within 2 to 4 weeks.

Frequently asked questions

Why doesn't my vet use the same suture for every layer?

Each tissue layer has a different healing timeline and functional requirement. The subcutaneous layer heals in 3 to 4 weeks. The linea alba takes months to reach full strength. Matching suture absorption rate to healing timeline is what prevents premature closure failure.

Are absorbable sutures weaker than non-absorbable?

Not at placement. Most absorbable sutures are placed with equivalent or superior initial tensile strength compared to non-absorbable materials of the same size. The difference is what happens over time: absorbable sutures lose strength as they dissolve, which is intentional.

I can feel a hard lump under my dog's incision. Is a suture failing?

A firm knot under the skin is most likely a buried suture knot in the subcutaneous or intradermal layer. This is normal, especially in the first 2 to 4 weeks. It should gradually soften. A soft, fluid-filled swelling is more likely a seroma. A painful, warm, firm lump may indicate infection. Contact your vet if you're unsure.

Choosing between absorbable and non-absorbable sutures is not arbitrary. Every placement decision reflects what the tissue needs at that depth, on that timeline, under that amount of tension. When the right suture is matched to the right layer, the result is a wound that heals cleanly without the complications that bring patients back for second procedures.

Resources

• WSAVA 2016 Congress (VIN). Suture Materials. vin.com
• Veterian Key. Selection of Suture Materials, Suture Patterns, and Drains for Wound Closure. veteriankey.com
• Veterian Key. Surgery of the Abdominal Cavity. veteriankey.com
• WCVM University of Saskatchewan. Lab 6 Part 4: Incision Closure. wcvm.usask.ca

Tissue adhesives surgical glues are a legitimate wound closure tool in veterinary surgery, but not a universal replacement for sutures.

Knowing when they are appropriate, when they are not, and what the evidence shows helps both clinicians and owners make informed decisions.

Quick answer: Cyanoacrylate adhesives suit short, low-tension skin closures, especially port-site incisions and minor lacerations with subcutaneous sutures already placed. Tissue adhesive alone is insufficient for high-tension or contaminated wounds.

Key takeaways

• Cyanoacrylate is the most common tissue adhesive, polymerizing on contact with tissue to form a flexible, bacteriostatic film
• Tissue adhesive alone is insufficient for longer or high-tension incisions: subcutaneous sutures must first take the mechanical load
• PMC study: intradermal suture had better cosmetic, clinical, and ultrasonographic outcomes than tissue glue in dogs
• No dehiscence occurred with tissue glue in the PMC study when subcutaneous sutures were placed first
• Longer-chain cyanoacrylates (butyl, octyl) cause less tissue inflammation than shorter chains and are preferred for veterinary use
• Application is significantly faster: 2 minutes 16 seconds vs 15 minutes 37 seconds for intradermal suture in one PMC study

What tissue adhesives are

SustainableVet: "Tissue adhesives are special glues used to close wounds or surgical incisions in animals. They form a strong bond that holds the skin edges together while the tissue heals underneath.

These adhesives are made from biocompatible materials safe for pets."

SustainableVet: "Cyanoacrylate adhesives are widely used due to their fast bonding and strong hold suitable for skin closure in pets."

How cyanoacrylate works: when the adhesive contacts tissue moisture, it undergoes rapid polymerization a chemical reaction that turns the liquid monomer into a solid polymer film in seconds. This film bonds the wound edges mechanically and creates a flexible seal.

Formulations: cyanoacrylates differ by the length of the carbon chain attached to the ester group.

NCBi (cyanoacrylate study): "Longer carbon chain cyanoacrylates (butyl and octyl) promote a less intense inflammatory reaction, with greater collagen deposition and greater tensile strength, requiring less time for healing."

Short-chain cyanoacrylates (methyl, ethyl) cause more tissue inflammation. They are used in hardware and household applications but not appropriate for veterinary surgery.

Medical-grade butyl and octyl cyanoacrylate formulations (e.g., Vetbond, Dermabond equivalents) are the appropriate products for clinical use.

Evidence from comparative studies

PMC study: tissue glue vs. intradermal suture vs. staples in dogs

PMC (wound healing study in dogs): "Glue had a less favorable outcome; intradermal suture was the best, though not significantly better than staples, which were applied easier and in significantly less time."

The study also reported: "No dehiscence occurred to the incisions closed with tissue glue.

PMC notes that subcutaneous sutures placed first may have prevented dehiscence: some studies report increased dehiscence when tissue glue is used alone without subcutaneous support."

The timing: stapling took a median of 21 seconds, tissue glue took 2 minutes 16 seconds, and intradermal suture took 15 minutes 37 seconds.

Feline ovariohysterectomy: tissue glue vs. sutures

PMC (feline closure study): "No statistically significant difference in wound dehiscence" between tissue glue and simple interrupted sutures in cats held in a semi-free environment compared to confined animals.

This suggests that tissue glue, when applied appropriately to properly supported incisions, can achieve comparable dehiscence rates to external sutures though the cosmetic and healing outcomes still favor intradermal suture.

Human meta-analysis (low-tension face/neck wounds)

NCBi (meta-analysis): "CTAs offered better cosmetic outcomes by Wound Registry Scale at less than 1 month. The cosmetic outcomes were comparable between 1 and 3 months.

Sutures exhibited superior cosmetic outcomes compared to CTAs at 3 to 12 months."

The early cosmetic advantage of tissue glue in low-tension wounds reverses over time. For wounds where long-term cosmesis matters, sutures remain the stronger option.

Laparoscopic port-site incisions in dogs

Wiley (canine laparoscopic ovariectomy study): evaluated n-butyl-cyanoacrylate for port-site incision closure. These are very short, low-tension incisions an ideal application for tissue glue.

High owner satisfaction and good cosmetic outcomes were reported for this specific indication.

When tissue adhesive is appropriate

Tissue adhesive performs best and is safest in the following scenarios:

Short, low-tension skin closures where the wound edges naturally appose without tension. Port-site incisions from laparoscopy are the clearest indication.

Elective closures with subcutaneous support: PMC data confirm that tissue glue over subcutaneous sutures (which take the mechanical load) produces reliable wound closure.

Minor lacerations: clean, fresh, low-tension skin lacerations where suture placement would cause additional tissue trauma.

Reduced-stress procedures: in cats or fractious animals where suture removal would require sedation, absorbable sutures or tissue glue that do not require removal are preferred.

When tissue adhesive is not appropriate

High-tension wounds: any closure that relies on the adhesive to resist significant mechanical pull the glue will fail. Subcutaneous sutures must take the load.

Contaminated or infected wounds: tissue adhesive seals the wound surface and traps contamination beneath the film. It should never be used on wounds with debris, bacteria, or exudate.

Deep wounds with significant dead space: dead space beneath tissue adhesive creates a seroma risk and an environment for bacterial proliferation.

Joints or high-motion locations: repeated motion breaks the adhesive bond. Incisions over joints or in high-flexion/extension areas require suture support.

Long incisions: the mechanical strength of tissue adhesive is limited. Longer incisions need suture support regardless of tension level.

SustainableVet: "Tissue adhesives are suitable for superficial skin closures but cannot replace sutures for deep or high-tension wounds requiring stronger support."

Application technique

Wound preparation: the wound edges must be clean, dry, and free of blood and fluids. Tissue adhesive does not bond well to wet surfaces or across contamination.

Edge approximation: manually appose the wound edges before applying the adhesive. The adhesive holds the edges in place; it does not pull them together.

Application: apply a thin, even layer along the wound edge. Do not apply deep into the wound itself only to the skin surface.

Wait for polymerization: typically 30 to 60 seconds. Do not allow the patient to disturb the site during this period.

Do not bandage tightly over adhesive: tight bandaging can lift the adhesive film before it has fully cured.

What owners should know

No suture removal: tissue adhesive dissolves as the wound heals, typically within 5 to 10 days. No removal appointment is needed.

Keep dry: moisture degrades cyanoacrylate bonds. Keep the wound dry for at least 5 days after application.

E-collar: even without external sutures, licking can degrade and lift the adhesive film. An E-collar may still be required depending on wound location.

The adhesive may crack or peel as it dissolves: this is normal. The wound beneath should be healing; the adhesive is no longer holding edges if the incision has adequately healed.

For suture patterns as an alternative, see interrupted vs. continuous suturing in dogs. For feline-specific suture considerations, see interrupted vs. continuous suturing in cats.

For site preparation that precedes closure, see surgical site preparation in dogs.

Frequently asked questions

Can tissue glue be used to close my dog's spay incision?

Not as the primary skin closure. Spay incisions require subcutaneous sutures first to close dead space and reduce tension. Tissue glue may then be applied over the skin surface; ask your vet.

Is tissue glue safe if my cat licks it?

Cyanoacrylate tissue adhesives are generally considered low-toxicity if small amounts are ingested. However, licking degrades the adhesive bond and risks premature wound opening. An E-collar is still recommended to protect the closure.

How long does tissue adhesive take to dissolve?

Medical-grade cyanoacrylate typically dissolves over 5 to 10 days as wound healing progresses. The adhesive does not need to be removed.

What if the wound opens after tissue adhesive is applied?

Contact the vet same day. A wound that reopens after glue closure may need suture reclosure. Do not reapply tissue adhesive over a wound that has separated proper wound assessment first.

Can tissue adhesive cause an allergic reaction in my pet?

Medical-grade butyl and octyl cyanoacrylate are biocompatible. NCBi: longer-chain formulations cause "a less intense inflammatory reaction." True allergic reactions are uncommon. Unusual swelling or discharge should be assessed.

Does tissue adhesive have any antibacterial properties?

Yes, minor. Cyanoacrylate polymerization has some bacteriostatic effect. This is minimal and should not be relied on for contaminated wounds; tissue adhesive is not a substitute for debridement or antiseptic lavage.

Resources

• PMC. Evaluation of Incisional Wound Healing in Dogs after Closure with Staples or Tissue Glue and Comparison to Intradermal Suture Pattern. ncbi.nlm.nih.gov
• NCBi. Cyanoacrylate Adhesives for Cutaneous Wound Closure. ncbi.nlm.nih.gov
• NCBi. Cyanoacrylate Tissue Adhesives Compared With Sutures on Facial and Neck Wounds: A Meta-analysis. ncbi.nlm.nih.gov
• Wiley. Efficacy of n-butyl-cyanoacrylate Tissue Adhesive for Closure of Canine Laparoscopic Ovariectomy Port Site Incisions. onlinelibrary.wiley.com